Rifaximin 550 Versus Xifaxan 550


In the US I am prescribed Xifaxan 550mg made by Salix Pharmaceuticals twice daily to prevent hepatic encephalitis (very dangerous disorder caused by liver disease). The problem is this drug costs $1,800 USD per month, which I cannot afford. However, through reputable Canadian pharmacies carry Rifaximin 550 mg made by Lupin Limited of Idia for only $130 USD per month. My best research seems to indicate that these are the exact same drug but that Lupin licensed the US sales and marketing rights to Salix, thus the dramatic price differential. Can anyone confirm that Rifaximin 550 is the EXACT same drug as Xifaxan 550? My life depends upon finding an affordable and safe substitute. Thank you for any assistance regarding this matter.

2 Replies

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Hello, Mark! How are you?

Yes, they are the same, Xifaxan is just a U.S. name brand for Rifaximin. However, it is not legal to obtain drugs from another country.

The FDA lists the typical side effects of this medication as possibly including stomach pain, nausea, gas, constipation, headache and dizziness.

However, the manufactured of Xifaxan does have a patient assistance program for those in need, so you may want to look into it and see if you qualify. You can call them about it at 866-282-6563.

Is there anything else I can help with?

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Verwon, thank you for providing me a direct yes/no answer to that question. I have tried the Salix assistance program but was declined because I have Part D medicare which does reduce my monthly out of pocket to only $650. However, I only receive $800 a month in medicare payments and I also have 4 other liver meds that I take.

I feel a bit like Jean Val Jean... To some it's a "loaf of bread", but to me it is life. Again, thank you for rapid response and your counsel.

Best regards,

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