Prolia Injection Side Effects (Page 2)
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Aprox 2 weeks after the prolia injection I started to experience nausea and weight loss. Also, loss of appetite and a keen sense of smell developed. It was difficult to eat or smell cooked food. It has been months and these symptoms have decreased dramatically. In contacting their website they would not confirm or deny this as a side effect of the drug. Has anyone else experienced nausea w/this drug?

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I had my second Prolia injection in April. This time I asked to have the injection in my tummy. It is so much better to get it there. I'm feeling completely better now as I have been tolerating the Arimidex well since after the first couple of months. The Prolia only made my arm sore. I might add that I had a mini stroke in April before the Prolia inj. Still not 100% from that. I have considerable numbness on my left side. I do get around though. Doing better each day. The medication for my breast cancer has taken a back seat compared to the stroke.

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I found some interesting side effects from the Nat'l Institute of Health today. We know that Prolia binds to RANKL; however, T cell helpers are bound and cause us to have the infections, hypersensitivity reactions and autoimmune diseases. The last one was amazing to me since my Doctor that gave me the inj did a lot of blood work and the results are back today. I now have Celiacs Disease, which means I cannot eat any food that has wheat, rye or barley in it. It's classified as an autoimmune disease. I only have one thing to blame it on - Prolia. They also wrote it was amazing that we are taking a drug to build up our bones which at the same time causes ours to break or die as in thigh bone fractures and osteonecrosis of the jaw. It further states that Prolia alone does not help our bones. It's the calcium and Vitamin D we are taking that help our bones. It also states that the jaw bone death from Prolia is causing infections in the muscle surrounding the bones of the jaw. We have pretty much discussed the remainder of the article here. This year is the big year for Amgen as Drs are Rx'ing more and more and more of this all over the world now. If your husband is using it as a cancer drug, stay far, far away from him or you will get Prolia without the inj. As I have stated before, it builds more bone but that new bone is very fragile bone. Not new healthy bone like they want us to believe. I'll be so glad when this is over and gone whenever that will be.

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You are writing about what happened a year ago causing problems now. No I had mine removed too along with all the lymph nodes. If you are not taking Prolia for chemo, stop it as soon as possible. It's a very BAD drug. It has zero to do with the cancer you had and makes cancer seem like a walk in the park. Check all of it's side effects. A few people here have done well with it but most of us have not. Also congrats on being a fellow survivor!!

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It has been 5 months now since my first Prolia inj. and I am feeling much better. Maybe one a week I feel puny, but no more vomiting as earlier. Will let you know how it goes after my second inj. in April. I now believe it is the Arimidex that has caused me to not feel well. A new complaint is numbness in my right hand. 11 lymph nodes were removed in the right armpit when the mastectomy was done last July.

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I had my first inj. Mar 4th 2015 and within 2 hours had tightness in my throat, ears and chest. Immediately took Benadryl which helped somewhat and put on my CPap and oxygen machine. Each day my symptoms have gotten worse and worse. Stomach pains, nausea, extreme weakness, trouble walking, terrific cough, headaches and neck pain. Went to ER and the ER Doctor gave a shot of Benadryl and sent me home. Apparently the only relief they could give me is a steroid which I am also allergic to. I see by others posts that their symptoms have gone on for the whole 6 month period. My left leg is becoming hard to use. My doctor tried to say it was "something else going on" but the ER doctor said it was the side effects of the Prolia. Isn't there anything I can take to alleviate any of these symptoms which I even left out a few!! I have been so sick!!

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I had my first Prolia injection on October 23 and on November 4, 5,6 & 7 I have had nausea. It seems to come in waves. Not a constant but serveral times a day. My husband and I were out shopping on Thursday, I became overheated, flushed, weak, dizzy and could barely move. Finally made it to a display tub, set down, husband went to check-out for a bag and I threw-up in the bad. Was so embarrassed, but could not go find a restroom. It just seemed as if I would pass out if I let go of the shopping cart. Once I vomited I became better and could make it to the lobby to have a seat. I still feel nausea each day. My doctor said I might feel "puny" for a couple but this is worse than feeling puny.

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Hi Bonnie,

From what I could gather, the following side effects are associated with Prolia, that may be similar to what you had experienced:

-nausea
-tingling in your fingers, toes, or around your mouth
-pain, numbness, swelling, or drainage from mouth, teeth, or jaw
-vomiting

Referenced from: nlm.nih.gov/medlineplus/druginfo/meds/a610023.html

You or your doctor can also report various side effects to the FDA's medwatch program at:
fda.gov/Safety/MedWatch/default.htm

Hope this helps!

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