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Phenytoin Sod Ext 100 Mg Cap And Grapefruit

Updated February 22, 2012
herman pickens Says:
Tue, February 14, 2012

does grapefruit metabolises phenytoin sod ext 100 mg cap?

1 Reply

1
David Says:
Wed, February 22, 2012

Grapefruit juice slows the breakdown of several drugs; however, information that I was able to gather on this topic puts phenytoin on a list of medications that have no significant interaction with grapefruit. Drugs in this section have all been studied with grapefruit, and found to have either a minimal/negligible interaction:
http:/­/­www.powernetdesign.com/­grapefruit/­general/­GJDIsummary.pdf

That said, grapefruit will have little (if any) effect on the metabolism of phenytoin.

I hope this information helps!

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