Oxycontin 10mg Er Not Working And Bad Side Effects (Page 2)
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I've been taking oxycontin 10mg for 2 years for chronic nerve pain after back surgery. I've gotten a few different kinds from different manufacturer's. I noticed that a couple of months ago that they didn't seem to be working. More pain, along with some pretty awful withdrawal-like symptoms. Also, they were coming out exactly the same as they went in. (not sure how to put THAT nicely-sorry!) After I did some checking, I found that the manufacturer was different. I did some research, and even contacted the company and sent some back, but they said they were OK. Yeah, right!! My next RX I got the old brand that HAD worked the months before. Now that manufacturer is not making them anymore, so now I'm taking another one. (They are all generic.) Well, it's happening again. More pain, withdrawal, etc. Has anyone else had this happen? And of course, you can't get a new RX cuz your dr. thinks you just want more. I never abuse them-I never take more than I'm prescribed. I just would like to know if anyone else has had this happen?? I sure can tell a difference. Thanx

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i have notcied different effects and adverse reactions wirh the 30mg roxy's , the white ones make me sick but the blue ones do the job , whatever that may be

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I would also like to add that you are not the only one who has noticed this type of problem with certain generics. If you do a search on the boards here, you will find a long post with many people who all had the same problem when they were switched from the name brand Wellbutrin XR to a generic version.

I had this happen recently with my Instant Release Oxycodone 5mgs. The previous capsules I had been getting were fine, they were made by Ethex Pharmaceuticals, however, last month, they gave me different generics made by Mallinckrodt and they do not work at all.

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The reason for this has to do with the actual reality regarding prescription medications. I know that they all say that generics are the same as their name brand counterparts, however, this is NOT necessarily true.

Truthfully, under the law, generics are allowed to differ in the ACTIVE ingredients from their name brand counterparts by as much as plus or minus 20%.

In addition, they do not have to be identical at all. To put a generic on the market, a company only has to prove that it is 'BioEquivelent' or that it works the same way in the body and does the same thing, even if the active ingredient is a different substance altogether.

You can read more details and you will also find the link the US law that permits this at this link:

Generic Drugs

So this, when you get some generics, you might not be getting as much of a dosage of the drug as you are supposed to be getting.

For some companies that have poor quality control, you could be get an even larger difference than just 20%. This is why Able Labs was shut down and all of their drugs pulled off the market a few years ago.

I hope this explains why you might be having problems with that certain generic medication and not with the ones made by the other company.

The best thing you can do to solve the problem is to always ask your pharmacy to fill your prescriptions with your preferred generic that you know is reliable. If they are unable to do so, call around to other pharmacy's in your area and find someone who has a decent alternative in stock.

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I really don't have an an answer to your odd response to a different generic form of oxy's, however I do have a suggestion for a different med,yes,I'm on it, Lyrica,which is for nerve pain. I have arthritis,fibromyalgia,etc. I got addicted to oxy's and they actually caused more pain than I am having now,off them.Maybe ask your Doc about this med, I have Chronic Pain also and they work. Good luck. P.S. You cannot just stop the oxy's, talk that over with him also.

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