Oxybutynin 15mg Extended Release
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Due to my spinal cord injury and paraplegia I use digital stimulation for my bowel program and therefor have the opportunity to feel some of the fecal matter as it comes through my colon. On at least 4 occasions I have found the Oxybutynin 15mg Extended Release tablets entirely intact. As an experiment I placed a tablet in a glass of water for 24 hours and after that time found the tablet intact except for the light coating that dissolved. The remains of the tablet had an almost rubber like coating. The tablet could be cut with a knife and the interior contained a white powder. It seems like the tablets are not dissolving. I have had to increase my dose to two tablets a day instead of one. In the past I was taking 5mg of Oxybutynin 3Xday. What is the mechanism for dissolving the tablets so they are “extended release”?

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Oxybutynin ER 15mg like many other time release meds will result in a "ghost tablet" in the patients fecal matter. The medication isn't there anymore. Do not chew or break or cut in half any ER, XL, or SR tab before consulting with your pharmacist. It could cause too much to be released at once and then none later.

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Maybe ask to try the oxybutynin transdermal patches :-)

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How did you solve this issue, my husband is having the same problem.

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With some time released tablets, it is actually normal for the shell of the tablet and some medication to remain intact and be expelled in your waste. Now all of these tablets are meant to be entirely broken down, nor are they meant to release all of the medication that they contain. In many cases, there is actually a little extra of the active ingredient in them, because your body can only absorb so much and variations in diet and stomach acid may affect how much of it is released, so they do this to make sure everyone gets the proper dosage.

That light outer coating is what is supposed to dissolve, once you swallow the tablet, to allow the medication to slowly release into your body. The rubber like coating is what helps control the time released mechanism. It is also likely that the white powder is part of it, but it could also be some of the active medication.

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