Nuvigil And Hormonal Changes? (Top voted first)

I've been taking Nuvigil for years, and never had any real issues with side effects, but I did a bit of research on what I've been experiencing in the last 6 months, and it looks like Nuvigil may be part of the cause. My periods are getting heavier and increasingly more painful, I'm breaking out like crazy, and I'm starting to grow some serious sideburns (well, peach fuzz, but I recently had to shave them, and it was A LOT). The combo sounds, to me, like the result of steroids, or androgens in general. I'm also looking into other lady-issues like PCOS, etc. I've let my doc know, and in the meantime thought I'd ask if anyone else has experienced hormonal side effects while using Nuvigil?

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Hi there,

Nuvigil is known to increase the production of some enzymes in the liver that metabolize estrogens and progesterones (why it can't be taken with systemic types of hormonal birth control). Is it possible that your typical estrogen/progesterone levels are being reduced because of this?

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Hello, Michelle! How are you doing? I am very sorry about the problems that you've been having.

No, that hasn't been reported with Nuvigil.

How old are you? Those are some of the early symptoms of perimenopause and that can start as young as 35.

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Agreed, that was my first thought. I discussed perimenopause with my GP a few months ago, and she ran some tests - unfortunately, not the problem. Wish it was, I would *love* to be done with that whole situation.

Thanks for the response - I'm going to check in with an endocrinologist as soon as I can, and my prescribing doc tonight, and I'll update this post for future searchers if I find out anything relevant.

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Michelle, just an FYI. Don't want to be the bearer of bad news but Perimenopause can last up to at least 15 years or more. Then Menopause can last just as long! I started at 36 and was still in that stage at 49 before I had a complete hysterectomy.

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