Norco Not As Effective

Hi, I have been taking Norco 10/325 1 every 4-6 hours for pain and Tramadol 50 mg as needed for breakthrough pain for over 4 years for Rheumatoid Arthritis, Psoriatic Arthritis and constant pain. However, I am starting to notice that I'm having much more frequent issues with breakthrough pain and it feels the Norco is loosing it's effectiveness overall. The pain has became so unbearable at times it really is affecting my quality of life tremendously. Please advise if there is another medication I can discuss with my doctor. Maybe something long acting so I don't have take so many Pills through out the day. Thank you

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It is normal for your body to build up a tolerance to any medication you have been taking for a long period of time.

There are higher doses of the opiate Hydrocodone that are available in a time released formulation called Zohydro. there are also others available, such as Oxycontin.

The FDA warns that these medications carry the risk of being habit forming and may cause side effects, such as nausea, dizziness, headache, constipation, and dry mouth.

How are you doing, now? Has there been any change?

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