Multiple Sclerosis Forums

I have had a nasty cold since starting Aubagio 4 weeks ago. Is this a side effect? I am 36 and was diagnosed with multiple sclerosis in 2004. I really have no support with my disease. ## Hi there Angela. I was started on Aubagio a week ago now and I also have had a continuous blocked nose as well as all over flu-like symptoms. My normal aches and pains have doubled in intensity as well, and don't even get me started on the energy and mood dip. ?? MS nurse had warned me of the side effects...but I didn't think I'd get them all at the same time. I have to really fight to keep motivated and I just hope to god that my body gets used to the tablets as quickly as possible, as I really couldn't take 6 months of this. ?? I'm sick and tired of feeling sick and tired. I'm ...

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I have MS and infuse with Tysabri. I am having severe muscle spasms. I am allergic to Lyrica, Baclofen, Methocarbamol, all prednizone drugs, etc. I take Dilaudid for pain as I also have a frontal-lobe brain tumor. I do go to a pain clinic, but my insurance BC/BS has denied my claim for muscle relaxants. Apparently, my pain clinic cannot prescribe Soma. I suffer from migraines and I am asking what can be prescribed for severe muscle spasms? Thank you. ## Hi Rae, sorry to hear about your pain. There's another thread on this site asking about Diclofenac in conjunction with Tysabri. I checked both the webmd and medscape drug interaction tools and nothing was listed between those 2 drugs. Have you asked your doctor about Diclofenac? I'd be really interested to know what they say. Alt...

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for multiple sclerosis ## I am not sure if the medication I have in mind is specifically for MS related pain, but from what I understand it is mostly for relapsing-remitting MS and secondary progressive MS with relapses. It is called Rebif, active ingredient Interferon Beta 1a. Is that what you have in mind or could it be a different name?? ## Rebif is a shot, not for pain but to help stop relapses in M.S. I have M.S., there is no pill just for pain for M.S. We use the same meds as anyone: Norco, Fentanyl, Neurontin, etc. ## Is Rebut used in extreme headaches due to a pulled neck muscle and severed neck vertebrae? If not, what is the suggestion? ## I have a co-worker that is killing herself with a pain med that I only know it starts with an R. She acts as if she is drunk and drives in t...

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I take Tysabri for multiple sclerosis. I am struggling with arthritis pain, as I can't take immuno suppresant therapy with Tyasabri. My only drug allergy is to sulfa. Is Diclofenac an option? ## I checked several interaction databases and none of them listed any problems with taking these two drugs together. Of course, the best judge of what is safe for you to use is going to be your doctor. ## What pain pill can help nerve pain from a severed arm, plus chronic ankylosing spondylitis? ## I receive a Tysabri infusion for M.S. - Can I take Diclofenac for muscle pain?

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I got off ampyra after taking for 3 months because I felt it did not help my walking and caused other problems. I was not happy putting up with insomnia but was willing to tolerate if it was a tradeoff with walking. Since being off the medicine for one week my walking is terrible and balance worse than when I started. Has anyone else noticed problems when they stopped taking medicine after a 3 month period. I still feel the ampyra did not help but do not understand why I am worse off now than when I started the med. ## Sounds like we had the same results. I tried Ampyra for three months, during which time my walking actually seemed to slow a bit. I stopped using it when I got a nasty UTI, which gave me symptoms similar to an MS exacerbation. It took two rounds of antibiotics to finally ...

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I read all about teratogenic effects for women who consumes Aubagio but I haven´t found anything in literature for men? How does Aubagio reflects on men semen, and do they need to pass therapy with active carbon like women if they are planing family? Konwing that spermatogenesis takes about 6 month.

since taking aubagio my big toe tips are red swollen and painful. Very painful. Could this be from the acid Aubagio creates; should I be concerned about gout? I already have elevated liver levels (after 38 days) of taking aubagio. Taking 2 more weeks and checking liver levels again. ## Hi, Candy! Actually, Aubagio can cause peripheral neuropathy, which could explain what you're experiencing. However, you need to consult your doctor to get an actual diagnosis and see if it is from the medication. Learn more Aubagio details here. I see the 2 weeks has passed since you posted this, how was the second check on your liver levels? ## my levels peaked at 135 and 142 during month 1 & 2 of taking Aubagio. Remained on Aubagio and the levels over the past few weeks have slowly gone down. N...

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I took Ampyra for 9 weeks--twice a day for one week but the insomnia was so bad my neurologist took me off for 1 week, then 1/day a.m. for two more months, but walking was worse, not better, I thought possibly because I was getting so little sleep Since stopping it 8 weeks ago my walking has gotten significantly worse. Over the past several years, my MS has been stable according to MRIs with walking deteriorating very slightly, but after stopping Ampyra, walking and balance are significantly and increasingly worse. I hope my MS has not kicked up again after all these years. In addition to insomnia, the most significant side effect was terrible stomach pains, way beyond the "indigestion" listed in the side effects, and I lost several pounds I didn't want to lose. That pain en...

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I took this drug in 1979 with my second child. My son was born 15 weeks premature and suffered many complications in the few months after. His lungs ruptured eight times, he had a whole in his heart and suffered bleeding to the brain. He is now 31 and is blind, suffers from cerebral palsy, mentally delayed. His blindness is due to the detachment of his optic nerve. I was told by acquaintances that his prematurity is a side effect from this drug. Is this true? ## I also took Benedictine in 1966 and 1971. My son was born 4 weeks premature and at 6 weeks of age was an asthmatic. At the age of 20 months he developed the Nephrotic Syndrome. This condition effects the autoimune system and he literally drowns in his own body fluid. At the age of 15 years it stopped due to mega doses of prednis...

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I got stuck by an SUV while riding my bike to the park. this has been over a year and with out health insurance i my back and left shoulder am in a lot of pain. Does anyone know of a good Dr. in Columbia ,mo , or mid-Missouri that will write pain scripts? thank you for your time guys. ## I had three car accident in over two and a half months destroy my shoulder my spine was already straight from previous car accidents is muscular dystrophy and multiple sclerosis and I'm meeting decided doctor there's them to just sitting there right for any opiate pain medications so I need a doctor so I can go back to work and have a life again

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I am on day 10 just started Gilenya with 6 other MS people. The first 5 days were fine then fatigue started big time sleeping 10 hrs a day, felt very teary, anxious and overwhelmed. By day 7 I couldnt stop the tears, no energy couldnt speak to anyone, felt so isolated and worried is this what my life is going to be like on this new ms drug? I have searched on the net ans some are saying it relieves depression? Im not on anti-depressants and I dont want to go on them, I go to the gym to keep me emotionally and physically ms at bay. Im 50 yrs old and have had ms since I was 19yrs Ive been blind and had every disability due to ms.. Ive been very lucky to over come every one.. My dilema now is secondary progressive lesions on my brain and my spine too many to count... Ive been lucky never u...

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This call center is HORRIBLE - don't they understand they are dealing with people with MS? What JERKS ## Hi, Deb! Very sorry you had problems when you called. Where they generally unhelpful, uniformed or was there some other problem? I've found that when I call the one I use, they are usually very helpful. I never had a problem until recently, when they were switching to a different company to fill prescriptions. Do they have a website you can use, rather than calling? ## I had the worst experience with the Ampyra patient assistant. It was the only phone number I had. My insurance specialty pharmacy sent out my Ampyra and teffedera in a regular cardboard box. Both medications arrived in bad shape. It is the end of June. Which means it is hot. The bottles were too hot to even tou...

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It worked for me initially for about 2 months, but experienced a sharp decline in my walking. Now my walking is wobbly with foot drop. Tripped a few times and fell. I've stopped taking it for the last 3 days and my whole body is drained and have no energy. Will it get better over time? I don't mind if it takes a longer time to recover as long as it does. I'm not expecting a 100% to pre-Fampyra state.

First of all, let me say that taking Ampyra has DEFINITELY helped my walking. I haven't felt the need to use my cane since almost day one. Speed, gait, balance all improved. Since insomnia has been an issue for me all my life, my Dr. suggested I just take one pill in the morning. I've been taking Ampyra now for 4 months, and still have only taken one pill a day, usually around 8am. That seems to working very well for me - is there any reason I SHOULD be taking the evening dose? Most evenings, I'm not on my feet much, so there doesn't seem to be much point. Your thoughts? ## Hello, Julia! How are you doing? I am so glad that this medication is working so well for you. If one pill is working for you, then no, you should go with what your doctor instructed and stick with yo...

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My aunt stopped taking Ampyra this am per her doctor. Dobyou know-how long before it will be out of her system. ## Hello, Suzanne! How is you aunt doing? It really depends on which aspect you're talking about, because there is a difference between when it may be processed out of her body, and when any unwanted side effects might go away. It only takes about 24 hours for it to be processed out of her body, according to the FDA, but some side effects could still linger for a week, or more, after stopping it. What caused her to have to stop taking it? The FDA lists its typical side effects as possibly including nausea, dizziness, headache, dry mouth, constipation, and itching.

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I have been taking Ampyra for 4 days. I have noticed a decrease in fatigue but headaches daily. The question is will they eventually go away on their own, or do I skip a day and see if they stop or quit til I see the doc ? ## Since last posting I have reduced amount to 1 per 24 hr. headaches are still occuring.2 Excedrin migraine seems to help.I have noticed an improvement in energy. ## I have been taking Ampyra for 4 days now I am feeling like the walking is slightly easier. My backpain has increased slightly but it isn't intolerable, it's ignorable. I'm liking. I have posted and will continue to post updates about my experiences with it on check it out if you'd like ## I have been taking Ampyra for a little over two weeks now, and I have experienced a marked improvemen...

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I quit Ampyra as I only saw a difference for a bit of time. I'm on LDN now and getting my dosage correct. Things improving, it takes time. ## I started taking ampyra 2 1/2 years ago, and initially I improved a lot, because of a mix up with the third timed walk, my insurance did not approve the refill for about a month and a half. I deteriorated rapidly and in fact began walking WORSE than before I started taking it initially. That month and a half without it, I started using a cane and although I improved a little after starting up again, I continue to need a cane. When I don't take it on time, I see a small difference in my ability to walk. I take it it in order to walk marginally better, but I'm way worse than I ever was before it. Knowing what I know now, I would have bee...

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I will be starting Gilenya in May. I have a 3 month washout period from Tysabri. I will be on Copaxone for 2 months. I was wondering how long it took to start Gilenya from the time they put the paperwork in. The nurse said must have aall the prereqisites done foirst not more than 1 month before and they will put paper work in 2 weeks before i am to start. Does this sound right. Thanks laurie f ## Gilenya contains the active ingredient Fingolimid, it is used to treat relapsing MS. It may cause some problematic side effects, such as: slow heart rate, headache, head cold and fatigue. As to the paperwork, the pre-requisites are actually more to do with your insurance/coverage than anything else, so I am afraid that I don't know anything about that. This medication has been FDA approved,...

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My level in this MS journey is - very weak and stiff on my left side of my body. I use a walker and wheelchair when going places. I started Ampyra about 3 months ago. Within 2 days I really started to feel it! I was able to turn over @ night in bed (I usually can't), I had more strength when I'd get up from a chair or sofa. Then about 3 weeks or so into starting Ampyra I had so many stressful situations happen in my life. Then I lost every good symptom relief I had. I know, I know... the drug works for some better than others.. blah, blah, blah. I just wanted to know if anyone out there can relate and if so, what was your outcome. Thanks =) ## Ampyra is a very new medication, just recently approved by thee FDA, it contains the active ingredient Dalframpridine. It is most commonl...

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was able to walk unassisted early in the day but had to use a walker later in the day. Neuro prescribed Ampyra, but when balance issue prevented walking unassisted at all after about a week of use, Dr. said to discontinue immediately. Balance issue continues for almost a year after discontinuing the drug and cannot walk unassisted. Could Ampyra possibly cause some lingering issues, even after its use has been discontinued for a long time? ## Hello, DJ! How are you? I'm more inclined to think it's due to an MS flare, rather than the medication, since it was discontinued so long ago. The FDA lists its typical side effects as possibly including nausea, insomnia, headache, weakness and stuffy nose. Are you on any other medications? ## Thanks for the response Verwon! The company (and...

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