Modalert, Modvigil, Waklert, And Artvigil Effectiveness?
UpdatedHas anyone tried these generic Modafinil and Armodafinil meds who can compare them to U.S. prescription brand name or generics? I know 2 of them are made by Sun pharma. I've had Sun pharma generic Adderall which was utter crap and another generic of theirs that seemed weak so no faith in them. The other is produced by HAB pharma which is another Indian company. Nothing against India in general, just their pharmaceutical industry culture is really bad and make cheap drugs often resulting in weak versions.
7 Replies
Modafinil If I remember correctly when I took this it was for MS fatigue It did nothing for the extreme fatigue it was suppose to help . for me it was just another junk med thrown at me I tried taking it for a month with so much hope huge let down.
Been a while. Have tried the Sun pharma modalert and waklert. And a generic prescription modafinil, I forget the actual brand of. Prescription worked better than the modalert. And modalert is stronger than waklert, but wears off far far sooner. But waklert is also 50mg less at 150mg.
Also tried the modafinilXL inhouse brands. Not as good as sun pharma brands. Still better than nothing if you don't have options.
I don't know the name brand of my adderall since my pharmacy doesn't list that , however I always ask for the orange oval ones if it a 20 mg and if it a 10 mg I ask for the blue pills , if not they will give me whatever ??? Last time they gave me these white ones in both 20 and 10 mg's and they were terrible !
Re: Purplegal (# 3)
The post was about a modafinil/armodafinil. Not Adderall. But, you mention orange oval 20mg and blue oval 10mg. That is most likely Teva brand. It is better to specify the brand since some makers can have similar shapes and colors as others. In which what is written on it will make the difference.
Most people agree that Teva or Sandoz brand are the ones that work the best. And the Teva generic is the exact same formulary as the name brand Adderall. Tell your prescriber to write Sandoz or Teva brand only on the script and you won't have to worry about it.
Been a while longer. Have now had a couple different brands of U.S. generic Armodafinil. Forget the names off hand. Were also Indian companies. Still a little better than the Sun Pharma internet Waklert. But, the Sun Pharma ones are still good enough to get the job done.
Re: myst (# 1)
Late reply to myst. Based on research the combo of an ADHD stimulant and modafinil or armodafinil would likely be best for comorbid ADHD and SCT. Which I can say for certain is far superior than any of those alone. And best thing is, cuts my Adderall dose, that ruined my life already with side effects, by 80% while being more therapeutic with less reduced side effects. Also, far superior for my narcolepsy as well.
I went the internet route as SCT is a decade or 2 from being ready for the DSM. And combing stimulants scares the hell out of almost all of them. In which I thing they should be reminded that they were taught how to titrate and monitor meds so shouldn't be an issue as done properly, negative response can be caught early and avoided. While combined meds have been shown can be superior therapeutically and as also demonstrated in my own experience, reduced actual side effects and even harm.
I was on strattera already, titrated modafinil, then when it was enough for a noticeable, but not even close to therapeutic effect, tossed in 1/5th my Adderall dose. Perfect, admittedly some luck hitting the sweet spot right away. More therapeutic, lasts longer, less side effects. Blood pressure and heart rate went down, the opposite of therapists expectations. But, was predictable with deeper understanding of how the meds work.
6 months later, and a total of 1.5 years of searching for any therapist that can help with high Adderall tolerance and side effects ruining my life, came across a neuropsychiatrist who actually works with people like me. And dumb luck has it, was familiar with SCT as his where he previously practiced, had people who researched SCT. So, confirmed that diagnosis. As well as confirming my medication approach as he has extra narcolepsy training. In which case narcolepsy has often been found to respond best to combined meds approach and was not afraid of a little titration if the patient did not have warning signs to avoid trying. Also confirmed the benefit of memantine that can provide neuroprotection from ADHD meds, especially the excitotoxic NMDA/glutamate damage found in research to be the primary cause of long term tolerance for those with dosage escalation issues. As well as protecting other pathways via the same mechanism.
And that covers a little under half of my medication approach as other factors not brought up in this reply, afforded specific attention.
Have more experience with US. generic modafinil and armodafinil prescriptions. Teva makes generics that are same as the name brand ones they also make. Sandoz also makes generic versions. Like Adderall IR, they are the best that I have tried. But unlike Adderall IR, I have found various other generic brands to be good enough and acceptable as Teva and Sandoz. They have been in shortage and unavailable for a while at my pharmacy. So, been getting whatever they can find. Do not know if there are other top working brands of the affinils, there could possibly be?
Adderall IR, Generally, but not same for every person...
Teva or sandoz are best.
Mallinckrodt is mediocre.
Elite is the exact formulary of the Lannette many people actually preferred over all before summer 2022. After which Elite dropped Lannett as marketer and marketed their own drug themselves. Lannett made their own formulary, which sucked like most other generics do.
For me, I respond to Lannett as not as good as Teva or sandoz, but better than Mallinckrodt. So, acceptable when my pharmacist forgets to put 'Teva or sandoz only' on my scripts. I won't accept anything else.
Shorrish explanation, inactive ingredients affect drugs ability to cross and stay across blood brain barrier. Amphetamines especially are sensitive. If anyone brings up bioequivalence or +/- 20% stuff, 99% of time they misunderstand it. Including me before I got skeptical and looked into it, Even then, not the actual issue. So ignore it and if curious, research bioequivalence and if it does not talk about AUC, logarithmic ratios, or 90% confidence intervals, your source is wrong. It is all about blood concentration over time comparisons which ignores the blood brain barrier. Which is the actual problem for psychoactive meds that have to additionally cross it to be therapeutic.
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