Methotrxate & Soft Spot

Probably seems a bizarre question but..has anyone noticed a soft spot on their scalp after using this.

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Oddly enough, this medication does list "hair loss" as a potential side effect. I would think that this is related to what you may be describing as a 'soft spot' on the scalp.

This side effect is listed here:
ncbi.nlm.nih.gov/pubmedhealth/PMH0000547/#a682019-sideEffects

Have you noticed any difference when not taking this medication?

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