Methotrexate - Liver Enzymes Elevated

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How long can Methotrexate keep your liver enzymes elevated?

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My doctor monitors my liver enzymes carefully. If we see a rise, we cut back on the methotrexate. I would rather have some pain, etc. from an autoimmune disease, than have problems with my liver. Liver damage is irreversible.

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While Methotrexate has been known to cause elevated liver enzymes, it has also been known to cause permanent liver damage in some people that take it, including fatty liver, fibrosis, and cirrhosis.

Ref: Methotrexate Information

What has your doctor advised? How high were they? Are you on any other medications?

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