Methotrexate & Coumadin
(Newest replies first)

Updated

I have the beginning signs of
Rheumatoid Arthritis and my doctor
has prescribed Methotrexate. I
have been on Coumadin for 13 yrs.
and I am concerned about the
interaction between Methotrexate
and Coumadin. Would it be a potentially dangerous combination?

5 Replies

Earliest Newest Votes
5

Re: Verwon (# 1) Expand Referenced Message

it does react just not directly. it should be listed. it can be taken together but as I replied above one must always stay in contact with their WARFARIN provider. only they. can tinker doses to keep your INR from going sky high causing. hemmorhage risk.

Was this helpful? 0
4

IT CAN INTERACT BIG TIME BY INCREASING INR LEVELS AND BLEEDING RISK! I have to take both. contact your Coumadin clinic or provider that monitors your WARFARIN. they will adjust dose and monitor you closely.This is directly from the doctors and pharmacists I talked to. The important part is to ensure you keep contact with your WARFARIN provider and methotrexate provider. if you don't have home inr monitoring ask your doctor. it's been a godsend for me!

Was this helpful? 1
3

I have been reading posts I am being given methotrexate for bullous pemphgpid have thoughts

Was this helpful? 0
2

I have come of these methotrexate 11 days ago was my last lot I took which was 6 2.5 mg can I have a drink now I have stopped these

Was this helpful? 0
1

I ran an interaction check for anything with those two drugs, there is a very good checker at drugdigest.org, they even check out food, supplements, and beverages. There is nothing at all listed between these two meds, so you should be fine.

Was this helpful? 1

More Discussions:

Methotrexate reaction

When I take Methotrexate (7.5 mg.) for my RA treatment, I get these swollen areas in the tissue, on my lower leg and som...

10 REPLIES
Methotrexate and skin problems

I've been diagnosed with RA. Been on methotrexate about a year then started getting skin problems, always at dermato...

7 REPLIES
Methotrexate and a chest cold

Hello, I take .6 ml methotrexate weekly plus plaquenil and sulfasalazine. I've been completely knocked out with a he...

6 REPLIES
Methotrexate side effects

I have been on Methotrexate and folic acid for 3 weeks. Started with three 2.5 mg tablets of MTX for two weeks, then up ...

5 REPLIES
Methotrexate and lupus

My daughter has lupus. How long does she need to take Methotrexate? Her hair has thinned as well. she takes it 1x a week...

4 REPLIES
Methotrexate a steroid?

Is the medication Methotrexate a steroid ? ## No, if falls under the DMARD category. (Disease Modifying Anti-Rhuematic D...

4 REPLIES
Methotrexate elevated Creatine levels.

Has anyone experienced an increase in their creatine level since taking Methotrexate or had any kidney damage as a resul...

3 REPLIES
Methotrexate - Liver enzymes elevated

How long can Methotrexate keep your liver enzymes elevated? ## My doctor monitors my liver enzymes carefully. If we see ...

2 REPLIES
Methotrexate injections for rheumatoid arthritis (RA)

I have just stated using methotrexate injections for RA after using tablets which gave me mouth ulcers and nausea. Have ...

1 REPLY
Methotrexate FDA black box

I need to know the FDA's black box for a transcript I'm working on for this medication? ## METHOTREXATE SHOULD B...

1 REPLY