Methadone 10mg Asc 116 (Page 5) (Top voted first)

What company makes these ASC 116 and when did they come out on the market?

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I definitely have plenty of experience with these issues. Having been addicted, for well over 12 years,before I was finally given the Methadone... I have terrible back and leg pain; sciatica and various lower back pain. Since I began taking the Methadone about 6 years ago, I have had all three of these brands. The Mallinkrodt is what I was started with. The 54 142 is what I would be given, once in a while, when I had to go to a different pharmacy, & the (Ascent brand ' or whatever it is' )- is what I had once or twice, when the other two could not be found.
I always go for the Malinkrodt brand, before I even consider any other brands. I have been going to the same pharmacy for all the years I've had this medication, & when THEY don't have it in stock, & may tell me that they DO have the 54 142's - & will get the former in, say, 2-3 days: I will actually wait till then. If it is something that is WAY too long to wait, and would be ridiculous to wait, then I will go with the latter... but if the only thing that is available is the ASC 116, I will try and go to various other pharmacy's until I at least find ONE of the other two. If I cannot, then I will reluctantly settle for the 3rd option (ASC 116). I've found that with the 54 142's & the ASC 116's - THEY are the ones that melt on your tongue practically as soon as you put them in, so you really want to try and swallow it as soon as possible, so that your not wasting like 1/3 of it on your tongue or in your mouth.
There ARE drawbacks, as well as positives, when it comes to the "Round" Methadone pills... namely, the fact that they begin to work within an Hour. (Actually for me, I have them down to EXACTLY 1 hour), but then they only last about half as long as the Rectangle one (Mallinkrodt). Whereas, with the Mallinkrodt one(Rectangle) - it will (for me) always begin to work in 2 Hours, & then ensues to work for practically the entire day. I know that some of us would like to take more than just the 1 or 2 for the day, but if you HAD to do this, & really had a very little supply; you can at least count on this one to not let you down for that entire day. I would even go as far as to say that, into the next day - you're still not going through any rough withdrawal. Esp. if you take it in the later afternoon, then the next day - if need be, you could go a while, before taking the next dose without having to suffer too much withdrawal... if any. If you happen to be inconvenienced & you have a very small supply - it's THIS brand that is the best to disperse around & take sparingly... not having to overtake them, to keep from feeling crappy.
Though, again, there are definitely those of us who DO want to overtake them, or at the very least - take them more than need-be; & if you HAVE the means and the supply, then you can do this w/out too much worry (other than - of COURSE - the worry of hurting yourself..... so in no way am I recommending doing that!!) So, once again - The Mallinkrodt (to me) is def. the best brand for a bunch of reasons. Chief amongst them: They last far longer. They are more stable and reliable. They're (to me, seem) Stronger & just more potent and steady. {Some downsides: 1. Once you go about 2-3 days without taking them, you begin to go into a more potent withdrawal... & after about 5 days, there is DEFINITELY a very bad withdrawal feeling; 2. They, above the other two brands, tend to leave you with worse constipation problems. This, as well as other issues having to do with bodily functions, are likely a result with the fact THAT they are the most potent, and long lasting.
The NEXT brand would be 54 142 (I think that is what they are); they work nearly as good as the Mallinkrodt, while they don't have the exact same potency and lasting effects - they are definitely the closest. 1. If you're looking for something to kick in for you as quickly as possible - than it would be this brand. With (the rectangle's), it takes about 2 Hours... with these, it takes between 45 mins. -to- an hour (for ME, it's always 1 Hour). It might even give you a bit of a better "peak", which may be like 2-3 hours after you initially take it, & it may last(the 'peak') about 30 mins. (sorta like a Percocet would) - as with the Mallinkrodt... if you're REALLY searching for things like "peaks" - then you MAY be a bit disappointed, though I guess there is one, maybe for about 10-15 mins, but it's really barely higher above what you feel during the entire (fully working) duration of the benefits from the medication. 2. Another upside is that you won't have as much trouble with constipation, as with the (rectangle one), though of course, as with any type of medication like this, there is always the chance of it... while the 'crash' and the 'withdrawal' is always bad, no matter what it is you take; I've found that with this brand it isn't quite as rough. Mostly, & likely because you really never get quite as "involved" as you do with the (Mallinkrodt - brand). (drawbacks: 1. again, if you don't take it fast enough, and let it sit in your mouth, there's a huge chance that you're gonna lose a good portion of it, as you WILL swallow part of it, you wind up having about 1/3 - 1/2 of it stick in you mouth, or you spit it out (unintentionally). As it will "kick in" in about an Hour, this usually doesn't stick around for more than 6 hours or so, before you're pondering taking another one; & Definitely, you're not going to wake up the next day & feel like you don't REALLY need to take another one... (though, I'm definitely NOT saying it is ANYTHING like if you were taking Percocet's or worse (Oxycontin's) - where you're thinking about taking the damn thing while you're still dreaming. THANK GOD it's not anything like that. I guess you CAN wake up, and not HAVE to take one, but just saying that with the 'Mallinkrodt' - you'll typically wake up next day and far less, be thinking about having to take one soon.
Anyway - the 3rd & final one, would be the ASC 116's. I'm not really quite as familiar with these as I am with the first two brands, but I DO have Some knowledge on them. They are MUCH like the 54 142's - in many of the same qualities and lack there of, I mentioned... Same (will melt on your tongue fast); same (works in about an hour); (same - works for a much shorter amount of time than Mallinkrodt) - & (same, less of a lasting 'bodily impotence' issues -- having to do with Constipation, & other bodily things, & genital related issues). I HAVE found that they seem to do SOMETHING, with energy... like they have caffeine in them ore something (which for me, is NOT a good thing -- I don't do well with "pick me up type things). I could be wrong, but usually I can pick up if I took something that has ANYTHING that gives me, or affects my energy or whatever. And it's never good (that's why I can tell, because I don't feel right). Anyway, with these, it seems to me that they are the least affective ones. As someone had mentioned before, there are active ingredients & also 'in-active ingredients... & I FEEL like with this brand, there are much more "IN Active" ingredients involved. What they are, is the question (especially as opposed to the other ones... I believe that RIGHT IN THERE, lies the problem or solutions. I didn't really get all into that aspect, but it's also something that is pretty prevalent.
LASTLY, (which should have been firstly, and mostly) - there is the pain relieving aspects. Definitely, Mallinkrodt(rectangles) work well with pain, & in them is (I believe) the best pain management meds.
The 54 142's - also work well for pain. But, as ONE of the reasons why I hold out for the other one first - it's not really quite as good as the (Mallinkrodt/rectangle); Maybe it has that 30 mins of time where it relieves pain better than any of them, but overall throughout about 4-6 Hours (to start with), this one is 2nd Runner up. But it isn't really al THAT bad. I wouldn't turn it down stone cold, & especially if I was just trying to have something for the pain ALONE; I was in all kinds of bad pain & nothing else was there to be filled (it's No question - I fill it).
The 3rd one, as far as pain reliever... I can't really answer that one all too well. To be honest, I had a few of them put into my filled prescription, & after taking the first-mentioned ones, I wound up taking these (same day) & I could tell you that I definitely felt some strange feelings. It seems like with them, you are more amped (or something along those lines). It actually seemed to TAKE away, from the GOOD ones, I had taken earlier in the day, but AGAIN - it COULD all be in my head; as I mentioned, I really don't know much about them... aside from that they're SUPPOSSED to be the SAME EXACT thing (same MG's/ Same strength/ same effect/ and same Duration) - as the other's. This is something that I just TRY and believe, and just TRY and tell myself, but it's hard, because it just seems to feel different. I can't sit her and LIE ( that last one "ASC 116" - it just SUCKS! (period).
(IF it were the LAST brand of this on Earth, though, I WOULD take it, but I'd be pretty miserable about it).
VERY SORRY for this being longer than crap... I thank you if you had the patience to actually read through it, & I definitely appreciate if anyone would want to comment back on any of it, especially if you saw some things in there that you yourself thought, the same way (or even if you didn't).

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Well it is nice to know that I am not the only one to think that the asc116 methadone are not working like the other brands my wife thought i was crazy but I knew that there was a big difference in the i guessing the amount of narcotic

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Ascend is the worst methadone in creation and I've got 45 years of experience to allow me to honestly state this. They should be pulled from the shelves! NOW!

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Not exactly true, or else so many people would not notice differences in not only this medication but various others of different generic brands. Quality control may not be as competent from one laboratory as another, which leads to the precise dosage being as much as 10% higher or lower, generally lower. An example of this which can be researched is in the popular pain medications such as Oxycodone tablets. The Oxycodone and Roxycodone 15 mg. tablets have been found to not contain 15 mgs. of the active ingredient but actually contains 12 mgs. of Oxycodone, manufacturers of this particular pain reliever have confirmed this to be true. Also, the reaction to medications, especially medications such as opioid pain relievers may cause the patient to feel quite differently if switching brands, this is caused by the chemical structure of the drug, if the chemical structure varies only a small amount then the patient will feel differently than the same medication and dosage of the previous brand that the patient may have been taking for several months or years. I've noticed this firsthand with 2 different pain medications that I received from the pharmacy when they ran out of the usual brand I always received and substituted it with a generic. the 1st time I noticed this was when I had been taking 10 mg. methadone tablets made by Roxane laboratories and instead received the generic brand 'Dolophine" 10 mg. tablets. The Dolophine were a bit smaller in diameter and the feeling I felt after taking my normal prescribed dosage was very different psychologically.

The 2nd time I noticed a significant difference in another opioid pain reliever I had been prescribed for "break through" pain. I had always picked up 15 mg. Oxycodone tablets manufactured by Mallincrodt and the pharmacy was out of my usual brand one day and substituted a generic brand "Mylan." The Mylan tablets were larger and much stronger than the Mallincrodt. Ever since then I began asking for the Mylan brand and once they ran out of those I couldn't get them again at any pharmacy and the reason this began happening is because I wasn't the only person that noticed the difference, and as a result most pharmacy's refused to carry Mylan Oxycodone tablets because they viewed the sudden preference as "drug-seeking" behavior, forget the fact that everyone had a legitimate prescription and the Mylan brand was more effective for pain, many pharmacists, doctors, and of course law enforcement agencies didn't want the patient to have any say-so on the medications they received, and if they thought the preference was about "getting high" then society can't have that at all. I hope these stuffed shirt, so-called professionals never have an injury, or chronic pain condition that requires them to use and opioid pain medication to treat their pain and make it possible for the patient to function better in their daily lives because the medication is therapeutic for most who do suffer from a chronic, or terminal pain condition, because then they will understand what it's like to be discriminated against by the medical and law-enforcement community, and the personal and ignorant bias these types of people have that causes the already suffering individual patient to suffer even more.

Now to address the second part of the posts that indicated instant sickness allegedly experienced from a different brand of Methadone as if they are suffering from withdrawal. Methadone has a 24 hour half-life and even if you abruptly stopped taking Methadone you would not suffer from "withdrawal symptoms" for at least 3 days, unless you had taken some other medication that caused the Methadone to be flushed from your body such as Suboxone, and Subutex as well even though Subutex doesn't contain Naltrexone, a,k.a. "Narcan." After approximately 3 days of stopping the use of Methadone the patient will begin to have sleepless nights, interrupted sleep, nightmares and night sweats, depression, extreme fatigue, loss of appetite, and in some cases seizures, although rare, and in older patients who are in bad health or suffering from cardiovascular disease, the patient can even die. This has been seen in jails across the country who unlawfully refuse to give the prisoner their prescribed dosages of methadone. All these factors can be exacerbated by the patient also being on other prescription meds, such as benzodiazepams. A patient who has been taking Xanax, Valium, and other Benzos for several years can suffer a horrible and lengthy withdrawal if they should abruptly stop taking these medications as well, some patients can also die from Benzodiazepam withdrawal.

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Im a med tech so alls i do all day pass medication!!! U are 100% right. 10mg of one pill may not be 10mg in another manufacturer! Ive seen 100s of times when a manufacturer is switched and us nurses and med tech and patients know and can feel a difference

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Folks: What can we do about the ASC issue? Im tired of being told " tough crap, take what you get or do without " So far CVS has had Roxane brand and I have been feeling ok. But I feel so bad for others who have no choice or cant get a decent brand. Pharm techs- help us out..who can we contact about this without sounding like crybaby dopers???

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mallinkrodt brand rules next to diskettes.

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Amen! My pharmacist has labelled on my chart, mallinkrodt only, and he orders ahead of time. 25mg s day. Saved my life.

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WELL SAID I AGREE WITH YOU 100% I WAS A COMPOUND PHARMACY TECHNOLOGY UNTIL A FEW YEARS BACK WHEN I WAS ASSAULTED AND BEATEN TO WITHIN AN INCH OF MY LIFE. I AM NOW DISABLED AND STRUGGLE WITH THE SAME PAIN YOU DO AND WHILE WORKING AS A COMPOUND TECH. I REALIZED THAT WHAT YOU SAID IS SO TRUE WE ADDED A CERTAIN AMOUNT OF ACTIVE INGREDIENT AND CERTAIN AMOUNT OF INACTIVE INGREDIENT BUT HEY GUESS WHAT THE AMOUNT YOU CAN BE OFF OF THE ACTIVE INGREDIENT IS FAR LESS THAN OF THE INACTIVE INGREDIENT. SO WITH THAT BEING SAID YOU COULD PUT MORE OF THE INACTIVE INGREDIENT IN THE PRESCRIPTION AND STILL CALL IT THE SAME. ITS BS IF YOU ASK ME. THE MANUFACTURER ARE JUST AS BAD AS THE STREET DEALERS WHO CUT THERE DRUGS WITH BABY LAXATIVEAND KEEP MORE OF THE GOOD STUFF TO MAKE A HIGHER PROFIT. ITS ALL ABOUT THE MONEY. AND WHO SUFFERS WE DO THE CONSUMER'S. KEEP UP THE GOOD FIGHT AND GLAD YOU ARE FEELING SOMEWHAT BETTER.

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I agree I've had to take methadone for several years now and these ASC's are the worst. I can not up the dose without the Dr.'s ok and hes a new dr. for me so I better not start off with issues so I wind up in pain and suffering. I doubt theirs anything we can do the pharmacy says there just as good so until the pharmacy's get better meds we will all suffer.

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I have taken every kind of methadone that they make. I have a really high dose(280)split because my peak and trough was really low. I went on vacation and had the ascend pills for 2 weeks and i had no problem whatsoever. What you should do is try not looking at what brand they are and just take them i didnt have any problems ingredients are the same in all forms I just compared them.

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Just so people don't say I don't know pain, I was in a humvee in Iraq and 3 120mm mortars exploded under it and blew me 25 feet in the air broke my back my right arm and elbow and my left ankle knee and hip and I have taken all forms and I haven't had withdrawal symptoms at all.

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To say it's the same is just not true....the facts are the active can be 10% different and inactive 20% to say that is the same is inaccurate ......my point I just took the medicine my body and head is what told me there was an issue ......they wanted to increase dosage ......when I started taking methadone manufactured by malinkrodt pharmacy which has been almost 3 months back to no issues.........so yes I am a believer the facts is what I use

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Ian Bruno. What is so different. About. 116Asc u think if. U did not see asc116 and the hospital. Gave it to u would. U be able. Tbo tell I think if it was 100 mg u would. Get straight. What. Do u think

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I just got nasueas myself .have been all morning ..somethings wrong with these pills

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I have been on methadone for fifty years. Have taken about every kind there is.. Presently am taking 175 mg. of red liquid. Top dose has been 250 of yellow biskets
(really diskettes). Over the years have been in hospitals and taken every variety of white tablets; triangles, green. Methadone is methadone is methadone. I don't care what color shape or format (liquid vs. tablets). It's always been right. For fifty years I've been hearing, This stuff isn't holding me. Relax. You can think yourself into withdrawal.

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Thank god your not a doctor someone educated to the hilt should be able to construct sentences and use proper grammar before claiming how educated they are, lets go very slow now kindly enthrall us with your acumen ( that means educate us)we want to partake in your vast array of pharmaceutical knowledge lol

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Most have that very same reaction. In fact several folks on high dose long term methadone maintence treatment have reported precipitated withdrawal syndrome. That is hell in anyone's estimation. Even dosage increase has little effect. Wish I could recommend something substantial since neuropathic pain is a b**** to control with the very best of rxs available. Hang in there.

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'Warning do not abuse' is what they should put on the bottle.

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I find that the methadone is stronger and lasts longer. I take 10 mg 3 x a day. I can take the three and not need to take it the next day. I also dry out every month for the last three days before getting my next prescription. I find it works better then the other pain meds. I tried them all to detox methadone. I have done it at 100, i dropped 5 mg a week until it was down to 5mg and then I stopped. I had marijuana to help for the few days after. Good for mental health really. Good luck. That was 20 years ago.

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Ok I've been on Methadone since 2005 & I've never had blood pressure problems until now ... I was just curio...

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How long do these pills last? I'm on 100mgs of pink liquid methadone from a clinic & I also got the tablets, so ...

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Upon taking this med,it started to dissolve in my mouth by the time I got water in a glass and put it to my lips to swal...

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My aunt just received these pills from pharmacy and she wanted to know all side effects before taking medication. ## AN ...

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what is the difference between the round and the rectangle 10 mg methadone pills? ## Probably just the manufactured, how...

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is there any difference; longer lasting, stronger, etc. in the 54 142 and the 57 71 10mg methadone ## Both of these pill...

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White rectangular pill with rounded corners, 57 imprinted on left, 71 imprinted on right, M inside a square on the flip ...

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i want to take the real methadone out of the bottlesd trade it for somthing that looks like the real thing ## tan capsul...

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Need a doctor to prescribe, not a methadone clinic. I currently exhausted all in the surrounding areas. Very important. ...

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Are they scorn in different places on the back side of the pill? ## Hello, Jimbo! How are you? I'm sorry, but I am n...

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