Metamorphine Side Effects

Does this medicine cause constipation / piles?? Taking these tablets from 7-8 days and now I have constipation. Is it due to the side effect of this medicine?

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sili - I assume you are referring to the drug Morphine, which is an opiate pain reliever. If I am correct, then yes, constipation is a side effect of this and other drugs in the opioid class.

" Common side effects include drowsiness, vomiting, and constipation...

Side-effects of nausea and constipation are rarely severe enough to warrant stopping treatment...

Like loperamide and other opioids, morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. The gastrointestinal effects of morphine are mediated primarily by μ-opioid receptors in the bowel. By inhibiting gastric emptying and reducing propulsive peristalsis of the intestine, morphine decreases the rate of intestinal transit. Reduction in gut secretion and increased intestinal fluid absorption also contribute to the constipating effect. Opioids also may act on the gut indirectly through tonic gut spasms after inhibition of nitric oxide generation... " [1]

I would recommend speaking to your doctor about this, as they may be able to prescribe or recommend something over the counter to treat the constipation, which is a normal side effect.

[1] Morphine Details

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