Lupin Lisinopril Pill Size Change

I take 10 miligram Lupin tables - have been taking them 2x a day for 20 years. Today, I opened the bottle and they were 1/2 the size. Same markings on the pill and container, same color, same manufacturer but 1/2 the size. I asked the pharmacy assistant about it and she said the company was making them smaller but they were the same. I asked how they were doing that - were they removing fillers? Why did they have so many fillers in the first place. She said she didn't know, but would transfer me to the pharmacist. I asked the pharmacist and she sounded like she had been asked what the weather would be like the next day - "oh, I don't know...yeah...I don't really know." I don't feel comfortable taking these.

REPLY

REPORT

Yes, in most cases they have changed the fillers they are using, so the size of the tablets change. The FDA keeps a pool of them that they can pick from and they can use any of them.

What are the markings on the pills you have? Can you please post back and clarify?

The FDA lists the typical side effects as possibly including nausea, dizziness, headache, increased urination, and hypotension.

REPLY

Was this helpful? 0

Has the 20 mg changed size I just picked up my rx they are little

REPLY

Was this helpful? 3

I also take 10 mg of Lisinopril. Have taken it for 10 years and had no trouble at all. All of a sudden they changed the size{smaller} and I have been having light headedness and am very shaky. I have gone to 3 pharmacists and they all look at you like your making this stuff up! I am happy to see someone else is experiencing the same thing!

REPLY

Was this helpful? 3

The new 20mg is 1 half the size and weight they were. How could they be the same dose? Unlikly. It defies logic and physics. The active must be less. CVS when asked gave the same filler excuss and said they would call the manufacturer for a explanation. That was 2 days ago. No CVS response yet. I have picture of new and old lisinopril pills side by side. They are clearly not the same.

REPLY

Was this helpful? 10

I also take 10mg of Lisinopril - Lupin mfg - daily, and yes, I also noticed this month's supply was smaller. I called my pharmacy (Walgreens), and the pharmacist said I was the 2nd person this morning who called to ask about it, and all she knew was that the manufacturer has decided to make it smaller. That's all she knew unfortunately. But she said it should not affect the dosage. I also went on the Walgreens website and used their chat feature, and the representative there told me, "That is the correct description for the tablets. I have actually heard this same feedback from other patients about the medication, so it must be that the manufacturer has changed the way they made their tablets, possibly making them with less inactive ingredients. However, we have double-checked the imprint, so you can feel comfortable that is the correct medication." Maybe, someone just needs to go straight to the source - ie Lupin - to get the answer on why the smaller tablet size. Hope that helps!

REPLY

Was this helpful? 5

I don't like the smaller version of the new Lisinopril tablet made by Lupin. What is the brand name for Lisinopril?

REPLY

Was this helpful? 0

Prinivil is the brand name for lisinopril. There are others.

REPLY

Was this helpful? 0

Prinivil and Zestril are the brand names for lisinopril. I also got a new Rx with new size and was concerned, I had a big problem with paroxetine by Lupin when it changed and found another brand. I went to CVS and paid more but they had 90 day supply of old Lupin lisinopril and I will watch posts online to decide what to do when it runs out.

REPLY

Was this helpful? 0

I also take 20mg of Lisinopril at bedtime and noticed several refills ago that the size had gotten much smaller even though the pill said Lupin and 20. Pharmacist had no answer. Last night I called in a refill and tonight after getting home I noticed two changes...not only did my pharmacy strangely give me a brand new prescription # when I clearly had a refill left on my "old" number, but also, my Lupin 20mg were strangely back to their original bigger size!! I will be headed back to the pharmacy tomorrow to check this out. Something screwy is definitely going on with Lupin. Almost seems like a big time error in their manufacturing and now they're trying to correct. Too many people experiencing side effects with the change (or error) to a smaller Lisinopril 20mg. Has anyone else found their 20 now back to the original size?

REPLY

Was this helpful? 4

Follow up to my post above. This morning I called the Lupin complaint line (800-399-2561) and the rep went into a whole scripted scientific reason for the change in size on the 10, 20 and one other higher dose sizes. Seems they removed all the fillers, or inactive ingredients, and leaving only the active ingredients. As mentioned in my previous posting, my new 90 day prescription was filled yesterday and to my complete surprise, I received the original larger size Lisinopril that I had taken for years before the change. I brought the prescription back to Walgreens today and had a lengthy chat with my pharmacist. He has confirmed that Lupin has removed the fillers and will continue to manufacture the new smaller size for those doses. There are many warehouses that stock Lisinopril and here lies an answer to why I received the former larger size. The pharmaceutical warehouse that serves my local Walgreens continues to have the formerly large size in stock and it all depends on which batch my local pharmacy receives from a particular warehouse. My pharmacist checked his shelves for the 20mg and found both the large and small sizes. The pharmacist said most side effects come from the fillers, so since I was concerned about this, I decided to stay with the smaller size pill. The pharmacist was kind enough to replace my recently filled prescription with the smaller pills. I didn't want to take a chance. Hope this is helpful to Lisinopril users.

REPLY

Was this helpful? 22

I've been taking lisinopril 20mg for years. Today I picked up a refill and the pills were a lot smaller. They are imprinted with 20mg on the front and lupin on the back. Should I take them?

REPLY

Was this helpful? 0

Did you take your Lupin 20 mg. I've been having nausea every since I started taking them. Just wondered if you had problems?

REPLY

Was this helpful? 0

I haven't found anyone who carries Prinivil in longer only generic drugs. Most carry Leg Manufacturing which is who makes Lupin.

REPLY

Was this helpful? 0

I started the smaller ones! My doctor said it would be fine. I've been nauseated, and dizzy every since. I'm calling tomorrow to see Doctor to make sure it's not something other then the drug. I also called FDA to file a complaint

REPLY

Was this helpful? 6

Same problem as others.new size 10 mg.lightheaded .anxious.a little bit more tired.

REPLY

Was this helpful? 3

This is exactly what happened to me. I was on the old Lupin lisinopril for 6 years with a water pill and no issues whatsovever. Now, I'm on the new version of the Lupin lisinopril and extremely dizzy every day. Not feeling right at all. I had to stop the water pill because the lisinopril was enhancing the dizzi effect and making it so I couldn't even work. Now, I'm just on the 10mg new small version of Lupin linsinopril and extremely dizzy. It can't possibly be the same as it was before. I will be calling my doctor tomorrow to see if I can switch to the Watson (non-generic) 10 mg. lisinopril. My mother takes this one and has no issues at all. It' unfortunate that a manufacturer would change a pill and cause so many who are on it to have such severe dizziness and other side effects they never experienced before.

REPLY

Was this helpful? 2

Loris and others,

There is no difference between the large pill and the small pill. I noticed the change and just wanted to make sure that the pharmacist did not give me the wrong pills which is why I saw these posts. All the manufacturer did was remove the inactive ingredients that made the pill larger. Inactive ingredients by definition have no impact on how you absorb the Lisonoril. The pill is dissolved within your stomach between 15 to 30 minutes regardless and the medicine enters your bloodstream in the exact same way. Lisinopril can cause dizziness regardless of the pill size. Also, as human beings we ALL (that includes me) are subject to psychosomatic reactions caused by the fear that the changed pill (for example) can cause us harm. A common misconception is that psychosomatic means "all in your head" but that is not true. The symptoms are real, but the cause of the symptoms is psychological (like the fear of the changed pill). This leads to a chain reaction of others saying that something must be wrong because "everyone else" is having problems. Again, a very human reacation that we are all susceptible to. And just so you realize that my intentions are to be helpful, I will give you a personal example. I fell and hit my head on the ice. About a month before, my brother in law had emergency surgery and almost died from a head injury that occurred months prior. I started to have headaches and thought the same was happening to me and I ended up getting an unnecessary CAT scan. After the doctor told me it all looked good, my psychsomatic headaches went away. Hope this helps someone.

REPLY

Was this helpful? 11

I have taken the 10mg lisinopril for many years now. 2 months ago when I purchased the medication the size of the pill was smaller. I took the pills and noticed that my blood pressure was rising, This concerns me very much. Is anyone else having this problem. I'm going to go back to my Doctor to see if she has heard anything from others. I don't understand when they make a drug that no one is having issues with and then they change it with no way back.

REPLY

Was this helpful? 3

No, I haven't had a problem with blood pressure while switching from the larger 20mg pill to the smaller size. Everything is suppose to be the same except the inactive fillers have been removed. My pharmacist said it's mostly the inactive ingredients/fillers that cause a side effect with any pill. In April, I was put on a couple of new meds for a new cardiac issue and needed to make an adjustment in the timing of my different meds so there'd be no interference. I moved the Lisinopril to bedtime and it works out just fine. For those people who say they're experiencing various side effects from the smaller pill, whether "psychosomatic" (as another person posted) or not, it might be worth trying to move your Lisinopril to bedtime, as well. Please post if it works for you.

REPLY

Was this helpful? 2

I was in it two weeks ended up in ER with BP numbers I've never came close to before. The did a cat scan too see if I'd had a stroke. I changed to another generic, and will see if it goes back to normal. My BP with meds is always 130/80. Always

REPLY

Was this helpful? 0

Re: Lori (# 83)

Yes, Prinivil is the name brand for lisinopril. That's why it's more expensive. You'd think after all these years on the market they'd be comparably priced.

REPLY

Was this helpful? 0

Re: Lil Dipper (# 82)

Yes, I've heard of Prinivil - good to know. Thank you!

REPLY

Was this helpful? 0

Re: Lori (# 81)

Yes, I tried the Watson as well. The blue one. It is better than the changed Lupin. Target was carrying the Watson. I use Prinivil now. Expensive but don't have to worry about inconsistency. These generic mfrs are lousy w/quality control.

REPLY

Was this helpful? 0

Re: Max (# 78)

Absolutely. I had a problem and posted about a year ago. I always took the Lupin larger pill and shaved off part. I am a small person and the 10mg was a bit strong for me. This worked very well in conjunction with taking a water pill (hctz). Then when it switched to the smaller size Lupin, you could no longer shave anything off and it made me feel not right. It was awful trying other comparable meds and I didn't feel like myself. I reported this directly to manufacturer. The fillers are necessary as they slow down the absorption. I have since had to take the 10mg and work my way up to that dosage. I'm definitely more tired at the end of the day, but it is controlling my blood pressure. This is not with the new Lupin pill, I switched to Activus manufacturer. It is a blue pill marked Watson and it's a 10mg. I take this with the hctz. It does appear to be working. Not my favorite, though. The reason they removed the fillers from Lupin is all dollars and cents. No other reason. I know many who were taking this former version and it worked very well. It's sad that the well-being of consumers is not first and foremost on the minds of pharmaceutical companies.

REPLY

Was this helpful? 1

Re: Brian (# 18)

Just came across your post. I had been prescribed the 20mg pill when it was larger, and was cutting it in half and taking the half pill per day (was all I needed as I hate taking more of any drug than needed) which kept my blood pressure around 130 over 78 which is good for me. When the mfr. changed the 20mg pill size to a smaller physical size, I have to take the whole pill (I take half in the morning and half at night), and my average blood pressure is typically 140 over 84 or 86, which is really too high In my opinion. I have to go back to my doctor and do something different. My point is, the smaller pill is a much weaker strength or flat does not work like the larger pill worked. I check my blood pressure fairly often, sometimes 2 times a day.

REPLY

Was this helpful? 1

Re: Max (# 78)

I had a problem with the smaller Lupin 10mg Lisinopril pill. Higher blood pressure readings than what I had with the larger pill, Talked to my doctor and she prescribed a 30 day scrip for 10mg pill specifically from Mylan. I have been taking it for about 2 weeks now and taking my blood pressure twice daily. I am now back in the normal range,

REPLY

Was this helpful? 0

Re: Lili (# 10)

The fillers also slow down the absobtion rate of the medication in your body which can effect some people who are more sensitive to changes. The pharmacy did not give you the correct info. Sure it is true that some people may have sensitivity to some fillers, this does not mean if they remove all the fillers that people have been used to, there will not be a problem. The only reason that the fillers were removed was $$$$$$!!

REPLY

Was this helpful? 0

Re: Lonnie (# 17)

This is not true - the fillers definitely make the absorption rate slower - why did they have them there to begin with? Everyone is different and a change can affect one person and not the other. You should research it. My son has Epilepsy and it took us 8 years to find the right combination and dose to control his seizures - a change like this could be catastrophic for him. In my state (CT) we have a law that Pharmacies have to give the same generic anti seizure medication to each patient with every refill - they cannot switch manufacturing brand. Obviously there is a difference.

REPLY

Was this helpful? 1

Re: Diane (# 75)

The big increase was in systolic pressure jump of 20-30 . Still trying to get cvs to give me a different manufacturer. Based on past 5 months I would say I believe the binding agent is not keeping a good level through the whole day. It makes peak and is flushed out in less than 8 hrs. I take at 6:00 am .if I work out in am pressure stays at around 127-130 over 70 pulse 70. Work out in pm pressure is 147-157 over 80 and pulse 88 short of breath . To many Dr. will not listen ? To their patients. I live with this body 24 hrs a day they see you once every few months.

REPLY

Was this helpful? 0

Re: Sue (# 3)

I am having the same issue so did you change the tablet

REPLY

Was this helpful? 0

I've been taking lisinopril 20 mg twice daily for several years, filling it through Walmart Mail-Order whose supplie...

17 REPLIES

I too just received the refill for my Mom's 10 mg Lisinopril tabs from Lupin Pharmacy,and have discovered they are h...

3 REPLIES

Are they now smaller? I'm concerned. Purchased a new refill and I'm finding the 20 mg pills are much smaller tha...

4 REPLIES

I was taking the TEVA Triangle shaped 10 Mg. The Drug store switched to a round white one with only a 10 imprinted on it...

7 REPLIES

I Have Lisinopril & Would Like To Know What It Treats ,What Time Of Day To Take It ... ## Hi Richie, According to NI...

3 REPLIES

I'm calling the FDA on Lupin Pharmaceuticals. I have been on lisinopril for many years. Once I started with the newe...

5 REPLIES

My doctor is switching me from 100mg 2x a day labaetlol to 40mg lisinopril 1x a day how do the doses differ or are they ...

3 REPLIES

I was prescribed 10mg lisinopril for 30 days and I did respond well so my doc said she would continue the lisinopril for...

3 REPLIES

Does Lisinopril manufactured by Lupin have gluten in it? I have had stomach pain, chest pain, and headaches with this pi...

1 REPLY

Is it possible the generic versions differ depending on which company produces the same pill. In Ohio, I took 40 mg. of ...

3 REPLIES