Hi Linda, as to your original question about a recall, I checked on FDA MedWatch and did not find anything about your specific brand of Losartan/HCTZ tablets (NDC 43547-425, manufactured by Solco) being recalled. Solco did have a recall of Valsartan/HCTZ in 2018 [1].

What you might be referring to is the Losartan/HCTZ recall from Torrent Pharmaceuticals [2], [3] ... but that is a different manufacturer and NDC code than what you originally listed.

Also, as far as where this drug is manufactured, it could vary. For example, Solco is based in the United States, but they could outsource their manufacturing or some ingredients from other countries. To be honest I don't know whether they source and manufacture everything in the US. In theory it shouldn't be of consequence since their drugs which have gone to the market are FDA approved.

I hope this helps!