Ip100 Effecacy

I have taken 10mg/325 for a number of years ,IP110 is inferior to M367 and certainly to vicodin or lortab.Dr.Oz brought to my attention that many generics of many drugs can have an efficacy of +or_20% value.My opinion after many years of use of this type of drug is most generics are inferior.I also feel because I am on medicare my options are limited.IP100 is the poorest generic I have been given to this date.

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Hi john bee,

It is true that the FDA permits generic formulas to vary by as much as 20% from the active ingredients in brand formulas. 20% is extremely sloppy in my honest opinion!

This means that if one generic has -20% of the active ingredient, another generic has +20%, that's a 40% difference in dosages, plus a different set of binders and fillers that effect the absorption rate/bio-availability! It's no wonder everyone reacts differently to these drugs.

I'm frustratingly surprised that doctor's and pharmacists don't mention this to their patients; since it's like giving you a completely different script with the same name.

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