Hydrocodone-acetaminophen 10/325 By Mallinckrodt (Page 10)
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My pharmacy changed my meds from the yellow 10-325 v 3601 norco to the 10-325 white m367 mallinckrodt. I've been taking the yellows for years with no problems. Today I started the whites and feeling dizzy, a little weak, kind of panicky. What is different about the two meds that would cause this?

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Yes, far too many people do repeat that same stuff, without knowing the facts.

For anyone interested, the details can be found under the Hatch-Waxman Act of 1984.

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No, I just hope to help others going through this same frustration. The generic drugs are not the same--and when online forums tell people that "they are all equivalent and it is all in your head", I need to say something. :-)

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Please don't worry about it. You have ever right to be upset, I understand. There have been many people like you posting recently. It is a shame and none of you should have to suffer.

I'm glad you found a place to fill it, though.

Are there any other questions or concerns?

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I was able to refill my prescription for the Qualitest (yellow tablets) and am getting used to the SIGNIFICANTLY lower dose again. But I am hurting, and I had to drive several miles to find a pharmacy that is still filling opiate prescriptions. I live in greater Los Angeles... so I hope that gives an indication of how ridiculous this is. It was pharmacy #14, which means I contacted 13 other pharmacies first who said they will no longer fill prescriptions of Norco since it was made a class II drug. I don't understand why people in pain are being punished because of the illegal actions of drug addicts. This is so wrong!

I'm trying not to be bitter--but then

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I do understand how you feel, they also keep changing things and making it much more difficult for many people to get the help they need.

I feel bad for everyone and wish there was something that could be done.

How are you feeling?

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Well, if I was an attorney, I would file suit or try to find some way to challenge this ridiculous FDA policy regarding generic drugs. It is dangerous to allow this much of a difference between generic drugs. Now, they've made it nearly impossible to even get the worst generics regardless of your level of pain or your situation. I'm just appalled and have lost all faith in our healthcare system. Every part of it is broken. And the FDA is at the top of this list of agencies that need reform.

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Hello, RhoRhoRho! How are you? I'm sorry that you have also been having problems.

And yes, that is correct, the generics are allowed to different from the name brand, in the amount of the active ingredients, by as much as plus or minus 20%. For most people, this is an insignificant difference, but for people that are very sensitive to medications, it can cause problems.

Issues can also arise when going from one generic to another, because they aren't required to measure against each other, only against the name brand. Thus, someone could have been taking a generic that had more of the active ingredient in it and then suddenly be switched to one that has less. Using your example, some might be experiencing a sudden jump from 12mgs down to 8mgs.

Are there any other questions or concerns?

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I have had the same problem in spades. I am in so much pain and they are making it harder and harder to get my medication. Regarding the generic drugs not working, I finally mailed samples of the Amneal Norco (which does nothing; may as well take an M&M) to the manufacturer and contacted the FDA about it. The FDA responded that they are "within legal limits" regarding the amount of the actual active ingredient (Hydrocodone). When I pressed the FDA rep, he explained that manufacturers are allowed to VARY THE ACTIVE INGREDIENT AS MUCH AS TWENTY (20) PERCENT IN EITHER DIRECTION from the brand name! So rather than 10 MG., you could get either 8MG or 12 MG per pill and that is just fine by the FDA!. Unbelievable. If I can help others, the Watson GENERIC (not name brand) works the best, has probably 10 MGs as advertised. Qualitest probably has about 9 MGs; it does take the edge off the pain at least. Amneal is useless. I find it hard to believe that they have even 8 MG. I'd rather take a 5MG Watson any day.

In any case, everyone will try to tell you that "it is in your head" and the generic drugs are all the same. They are NOT. And you are being lied to. Our FDA is shameless for allowing this to take place legally: A VARIATION BY AS MUCH AS 40% OF THE ACTIVE INGREDIENT IN GENERIC DRUGS. It is NOT in your head. Watsons are impossible to come by anymore. If you can get Qualitest, that is the best you can hope for. Sorry.

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Hello, Jennifer and Don! How are you both? I am very sorry about the problems that you're having.

There can be slight fluctuations in the amount of the active ingredients, from one generic to another, though as I said they are very slight and don't cause problems for most people. However, if you've been taking one from a specific manufacturer for a very long time, then suddenly switch, it could affect you more than other people that don't take it regularly. From the symptoms you've both described, my guess would be that these white ones are slightly lower than the yellow ones were.

Normally, since the differences are very slight, your body adjusts after about a week or so.

How long have you both been taking them?

This is a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

Another alternative would be to speak to your respective doctors about the problem and perhaps try a different medication.

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hi i take the 10-325 hydrocodone apap tablet malli and i was takeing the yellow 10-325 witch helped me i have a very bad back and spine problems the whit pills do noting but give me headackes and upset stomack i have been on vicodin for many years now that the drugs store gave me the white pills they do not work but make me sick what can i do?

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