Hydrocodone-acetaminophen 10/325 By Mallinckrodt (Page 4)
(Newest replies first)

My pharmacy changed my meds from the yellow 10-325 v 3601 norco to the 10-325 white m367 mallinckrodt. I've been taking the yellows for years with no problems. Today I started the whites and feeling dizzy, a little weak, kind of panicky. What is different about the two meds that would cause this?

REPLY

REPORT

Re: ThunderHeart (# 128)

My question was which manufacturer are you using - you stated the one you just picked up was fine - Im sure we would all like to know since so many of us are suffering I'm sure it would be helpful to all of us.

REPLY

Was this helpful? 2

Re: lisa (# 126)

No generics at this point. Ive had side affects from them all except Qualitest, but they are not making Norco and more.
Generics are being made in India and other dirty countries where the FDA does not watch over the making of medicine.
This should NEVER BE ALLOWED!! This is medicine!!

REPLY

Was this helpful? 3

Re: cliff j (# 125)

Thank you for replying Cliff.

REPLY

Was this helpful? 0

Re: ThunderHeart (# 119)

Please tell us which manufacturer you just picked up that doesn't make you sick anymore.

REPLY

Was this helpful? 1

Re: ThunderHeart (# 120)
I believe that I replied to you on another thread about a substance that I ordered that I thought would add back in one of the ingredients taken out by the manufacturers. It just did not do what it claimed. The ingredients were not as advertised. There is one more product that I may try and if and when I order it I will let you know how it worked for me. I will keep you posted.

REPLY

Was this helpful? 1

Re: cliff j (# 122)

The generics we are getting from India are pure garbage and are not effective!! They don't have the same screening process like here in the US. The FDA regulates the medicines here but not in foreign countries. Why is it allowed that medicine is made in foreign countries and then given to us here in the US!!?? It is trash!! This needs to be stopped!! Our medicines should only be made in the US!! That's why people ask for certain brands. The medicine made in the US works!! The IP medicine is made by an Indian owned company and it's total s***!! It made me so ill!! Nauseous, itchy, upset stomach, the same symptoms as withdrawal. Their xanax is just as bad. Garbage!! Amneal makes the worst medicines!! Who knows what the fillers are in this "medicine" that made me so sick. Are the test kits available to test the medicine to see what is in it and how much of the active ingredient is in it? I want this garbage tested!! I am so angry!!

REPLY

Was this helpful? 2

Re: Melody (# 116)

I agree 100%.I also have taken them for 20 plus years and the yellow seems to be the strongest which is why you now have to pay cash to get those at most pharmacys whether you have any kind of insurance or not and very few pharmacies even carry them period.The ip 110's have absolutely the least amount of pain relief possible and the white ones period are about the same,with the exception of the white short fat lupins which do provide some relief.But,pharmacys now want to know why we ask for a specific kind,even if it means getting them from a different pharmacy.Nobody wants to pay for something that is completly useless to use.

REPLY

Was this helpful? 1

Re: RhoRhoRho (# 3)
The manufacturer is, to my knowledge, allowed to LOWER or be off the effective ingredient by 20%. I am unsure WHY the Hatch Act in 1984 allowed this 20% discrepancy. I have never heard of any other group of manufacturers that has a special dispensation to just be "close" to what is stated on the label. These manufacturers have precise manufacturing equipment and they should easily be able to manufacturer a pill to the exact tolerances of the prescription. They seem to have no problem lowering the amount of the effective ingredients but in no case am I aware of the manufacturer raising the effective ingredient. If you have any evidence to the contrary please share it with us. Aside from the active or effective ingredient being lowered the manufacturers have removed, or severely reduced, other things from their pills (oxytocins for example) to make them less effective. These pain pills have been reengineered to make them less effective INTENTIONALLY. The manufacturers believe that if they are less effective that criminals will not take them on the street or steal them from their relatives or Pharmacies. In actuality the only people being severely affected are the chronic pain patients that have been taking their medications as directed and legally. Some for decades. I guess if they cannot get the real perpetrators of the problem then go after the "low hanging fruit" and by any means necessary.

REPLY

Was this helpful? 4

Look at ingredients on the manufacturer's website.

REPLY

Was this helpful? 0

Re: BL (# 112)

There is no such regulation of this in the foreign countries these medicines are now being made like India (Amneal brand) and china and all the other s***ty countries where there is no quality control. WHY IS THIS ALLOWED!!!?? THIS IS MEDICINE, not dish soap!! These pharm companies should be allowed to manufacture medicine in the United States!!! Not dirty countries like India!! This makes me so mad!! Ive gotten sick on so many generics!! They are all dog crap!!

REPLY

Was this helpful? 4

I posted here about 4 months ago about the bad side effects I was having from the Mallinckrodt 10/325. I also emailed the company with my complaints because the side effects were serious- sick to my stomach, nauseous, dizzy, itchy, can't stop sneezing and not a lot of pain relief. I don't like taking more, but the pain relief quality is very far down. And IT IS NOT because I'm building a tolerance. I stick to my schedule so I know when the medicine is not as effective. It is quite obvious what my body is telling me. The quality and effectiveness have changed a lot lately. I've been taking it for years and have noticed many negative changes to this once, very effective, medicine. The new batch I picked up July 10th are different once again. Right away I noticed a difference in the size of the pill. The big change is that it is not making me dizzy, itchy or feeling like I'm going to throw up anymore. Just an FYI for everyone.

REPLY

Was this helpful? 2

Re: Jacki (# 117)

Hi, I would get the name brand, non generic but haven't found a pharmacy after extensive research, that will fill it.

REPLY

Was this helpful? 0

Jennifer I was having issues when in another state for a short time (1year), the hydrocodone I was given was a maybe colour instead of white. A few months down the road I felt they weren't helping and my inflammation was much worse.
My son checked ingredients and I was surprised to see red dye. I'm allergic to red dye! Changed back to the white and had it out in my records. Maybe you can request your original also?

REPLY

Was this helpful? 1

Re: RhoRhoRho (# 9)

They sure arent the same.I have had to take them for over 20 yrs now and have taken everything from the yellow(wrks best) down to the ip 110's(totally useless) to take period.Theres not a white 1 made that i havent had to try but if i had to choose one,the short fat n358's made by Lupin seem to be the best white ones so far.

REPLY

Was this helpful? 0

I to take Norcos and they gave me the generics and I told them that they does not work at all and there's still gave them to me they're still still Distributing them out what is there that we can do to stop this spending our money for nothing

REPLY

Was this helpful? 1

Attention: Anyone Who Has Been RX'D Hydrocodone 10/325 w/ MFR: Mallinckrodt

Once again they are dispensing complete and utter crap Hydrocodone from this mfr. I am 100% convinced that this medication is almost completely devoid of narcotic (the pain relieving ingredient). I had the same problem 6 to 8 mos. ago and ongoing prior for a year whereas the med. was not even touching my pain at all. O.K., then for the past 4 mos. it seemed to work and was relieving my pain somewhat. Just got my new 30 day supply on Fri. 6/7/2019 and once AGAIN it's back to the complete and utter junk, in other words it's devoid of the 10 mgs. of the narcotic, it may contain, I'm guessing, maybe 2 mgs. per what s/b 10! It does absolutely NOTHING for my pain! I just filed a complaint online with the FDA and I am urging others who are experiencing this same problem to do so. Something is definitely going on, I seriously believe someone, somewhere is switching the legit 10 mg. pills out with black market pills and dispensing them to us. It's probably being done at the distributorship or perhaps inside the mfr. company itself, an employee or someone?? If you too feel the same way, please go to the FDA's online site and you can file a complaint. The manufacturer of these junk pills is: MALLINCKRODT. I have severe back pain caused from Spondylolisthesis, Spinal Stenosis, Scoliosis, Arthritis, A Fractured Vertebra, and a cracked tailbone. I suffer all the time and since we have this so-called, "opioid epidemic" I am only rx'd a lousy 3 hydrocodone per day, yeah, I know it's pathetic. I believe this epidemic ended at least 8 years ago, why the hell aren't they taking alcohol off the market or limiting the no. of bottles of beer, liters of whiskey one can purchase since it KILLS WAY MORE people than any rx. medication EVER has. Legitimate pain patients are suffering terribly and it's about time we RISE UP and do something. It's NOT our fault doctors prescribed narcotics to anyone who said they had an ache and didn't even have tests to prove they had pain, I cannot even believe how many young people were being prescribed strong narcotics, like Oxycodone or Oxycontin for simple every day aches, I don't know how a young person in their 20's can have severe enough pain to require heavy duty narcotics. Anyway, I totally believe that this epidemic is over and they've weeded out the fakers and abusers so there s/b no reason for people with chronic severe pain to have to suffer with weak pain meds., especially junk pain meds.

REPLY

Was this helpful? 3

I have severe osteoarthritis, degenerative disc diseasse, scoliosis, blah, blah, blah and just got to computer to see if anyone else is noticing a difference in their pain meds. I take Endo 10/325 by Endocet, Walgreens orders for me. I have noticed a difference as well. Having said that, all others upset my stomach horribly and I felt dizzy too.

So far, best I have found is Endo 10/325, only Walgreens will order, try that. There is so much competition with Pharma companies, the only way to make money is to put less of drug in, AND THEY ARE!! and more fillers. Do your research by going to company name and look at the fillers, YOU WILL BE SHOCKED and know why you feel ill. They put all kinds of GARBAGE in for fillers. It's the fillers killing people, leading them to other medical issues, not the drug, they have reduced it by up to 40% and the rest is fillers, anything that will stick together, drywall, cardboard, glue, etc. Do your research, took me a while, found the EXACT INGREDIENTS on their website. Need to be somewhat savvy on manipulating their sites, but you WILL find it. Good Luck, Sunset.

REPLY

Was this helpful? 4

Re: Kelly Sarraj (# 111)


Fillers and binders affect how a medication is absorbed. Fillers and binders affect different people differently. Some people are not as affected as others. A generic has to get a patient within 10% above or below the blood concentration achieved with the brand for the FDA to approve it.

REPLY

Was this helpful? 0

I been taking Norco 10/325 for 27 years , there is NO difference between generic or brand name ( yellow or white ) ... All have same ingredients.... Some people say generic Norco not as good as brand name .... It's ONLY psychologically

REPLY

Was this helpful? 0

Different fillers (adjuvents). I can't do dyes especially yellow! I heard actavis took over Watson's hydrocodone but supposedly CVS is only one that carries actavis? I gave up researching! Because the lies & ring around the Rosie!!! When i started mallincrodt it made me sick, real sick, come to find out it was oxycodone? Wt heck? I still get stomach cramps & chills for 15- 20 minutes after i take it!! Good luck! Always talk to your pcp!!

REPLY

Was this helpful? 2

I have been taking 5-500 acetaminophen for my rheumatoid for a few years now with no issues and good blood test results ...

4 REPLIES

I am super scared... I have taken a total of 17 hydrocodone 10/300 today. I read (afterward) that 90mg of hydrocone is l...

20 REPLIES

oblong yellow scored on one side with a V and the other side with 3601 ## what is the strongest hydrorodane ## The stron...

4 REPLIES

Can I take one hydrocodone acetaminophen 10 325 and one tramadol 50 mg together? One 10 325 does not help much. I do not...

7 REPLIES

DOES HYDROCODONE ACETAMINOPHEN 10 325 HAVE VICODIN IN IT? ## Vicodin is a combination medications that contains Hydrocod...

6 REPLIES

Don't ever get that ActaVas brand Norco 10 325 white tabs they do not work I had half yellow half white last prescri...

3 REPLIES

I have the worst neck pain. I think it is from sleeping wrong. I have a prescription for the hydrocodone acetaminophen 1...

3 REPLIES

what does the t mean in hydrocodone/apap 10-325 t ## Hello, Dog! How are you? That just stands for tablet, meaning they ...

3 REPLIES

I am recovering from back surgery and have the generic Norco 10-325. They have not been effective in the dosage of 1 eve...

1 REPLY

Can you please tell me if hydrocodone acetaminophen 10 325 T time is time re-leaf, and if not is their one that is.... #...

1 REPLY