Hydrocodone 10/325 Vs. Hydrocodone 10/650

I have suffered from cronic migraines for years. For breakthrough pain relief my neurologist has prescribed Hydrocodone 10/650. When I needed it, it worked well unless the migraine had developed to a complex migraine, then a trip to the ER was needed, and IV hydromorphon and phenergan seemed to do the trick. Now thanks to the new federal law, No more than 325 mg of acteomediphine can be in medications. Now my medication doesn't seem to be working as it once did! What can I do now, other than taking two pills, which I don't want to do at all! Help!!

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Hi Krisy,

Sorry to hear about your situation. I'm no doctor, but I do know of some other people who have decided to just take an extra Tylenol (Acetaminophen) tablet to make up for the difference in dosing.

On the other hand, you have to figure that Acetaminophen in and of itself must be highly toxic to the liver for the federal government to feel the need to step in and enforce that change in its dosage. That's something to take into consideration if you plan on using it for an extended period of time.

With that said, I think your best bet would probably be to start looking into some other types of therapy or natural/herbal-based remedies that can help with pain or at least lessen the severity/frequency of those migraines.

I hope this advice helps!

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