How Long Before I See Results?
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I was prescribed Lyrica today. Being the impatient person that I am, I was wondering the normal lenth of time before the medication starts working.

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32

I have fibromyalgia and been in pain for years, I'm hypothyroid. Do to having no thyroid. I'm on THR but it's not always good. I've been on Tramodol for pain for years, and it kept my pain tolerable with very little side affects. Moved to a new state and my New Doc wants me off of the tramodol and started me on Lyrica. Ive been on it for 2 weeks now, having blurred vision, constipation, and a little wt gain. She said all this will pass. I don't understand while she wants me to switch? Is lyrica less dangerous?

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31

I too have a lot of pain. Just found out its Mild nerve damage L5 spine. Doctor said usually people are not in that much pain from this. I also had a mri done just waiting for results. I hate pills but in extreme pain. She just bumped the lyrica up cause she is worried about permanent damage to leg due to walking funny due to pain. I know take 150 mg twice a day plus 100 mg at night.

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30

Have you tried glycerin suppositories? I've found them very beneficial and fast working.

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29

So did it work? I just started using and seen no result. I am on day 3 and need to feel beter.

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28

People with two fibromyalgia also often have orthostatic hypotension. Which means if you get up quickly and start moving around, your blood pressure will fall and you'll feel faint.

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27

Has to get in your system well. With me it starting working the fourth day. I started on 25 Mgs. Then had to increase to 50 two years later to get the same amount of pain relief. Then a year later 75 Mgs which is where I am now. At present, I've been on it 4 1/4 years. It doesn't relieve all the pain. I have to do my part and avoid foods that trigger fibro pain and migraine. I'd rather have pain control so that I can go out and about so I put up with the side effects of Lyrica.

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26

Miralax is excellent. But I've been on Dilaudud for several years and as good as Miralax is, I recently found that Walmart's Fiber Therapy capsules (same formula as Metamucil capsules) are the best thing I've tried. They are 100% Psyllium. I can't stand to drink the Metamucil powder in water. The capsules are easy to swallow. If your constipation is truly horrible, use a few Psyllium capsules along with a dose of Miralax. I think you will be as amazed and pleased as I was. Constipation from opiates is terrible, and I've eve used a prescription medication to alleviate it, but it didn't work.

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25

Have you tried Miralax for your constipation? It's a really good product. I wish you well...

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24

Hi my name is Neel I'm in kzn South Africa I've been on Lyrica 75mg for about a month now but no relief sometimes I take 2x75mg one at night and one in the morning.I suffer with pinched nerve sciatica I'm also on brazapam, mybulen and degronol, this as been on and off for abt 6years now. I have missed out on so many events I'm starting to think God doesnt exist. Please mind me for saying so but I prayed so much I'm only 39 do I've been this fro age 33.

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23

How much are you taking (milligrams ) how many times a day. How are you feeling? Side effects??

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22

How much are you taking?
How many milligrams, how many times a day?

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21

In my first post on Oct. 31, 2015 I mentioned I had very bad pain after my colonoscopy and that is why Lyrica and Imipramine were added to my usual 4 mgs. of Dilaudid QID. I suffered for nearly three months with these added shooting pains. After two doctors (my pain mgt. guy, his PA and my GI doc, I got the GI doc's PA. She concluded it was a musculoskeletal problem and prescribed 10 mgs. Flexeril (cyclobenzapine) TID. Two hours after my first dose I felt improvement. After three dose, the new pain was essentially gone! Three long and painful months cured, literally, overnight! In addition, adding the Lyrica 100 mgs. TID and 20 mgs. of Imipramine (Tofranil) to my regimen of Dilaudid (4 mgs. QID) has nearly eliminated the groin pain I've suffered with for exactly four years! I stopped the afterlife after a week because there was no need of it and the hangover from it is strong. I've gone to such detail because I think all chronic pain sufferers may benefit from hearing that my persistence paid off big time. My pain doc of four years had given up and was suggesting I try a pain pacemaker trial, Johns Hopkins or a trip to a special pain clinic in Florida for persistent groin pain. All of those choices would have been prohibitively expensive.

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20

i took lyrica for back pain 150mg twice a day and i was told to go up to 300 twice a day and when i started taking that i was walking down the step and my muscles gave out in my legs and i fell down the steps, reason why i mention that is to say if anybody takes too much that will happen..i fell out in the yard when walking my dog and i had to lay there till my muscles came back, while i waited my dog he laid down beside me till i was able to walk again..i fell again in the house, it was alright when i cut back but didn't help pain so i was put on hydrocodone and oxycodone.. i hope Lyrica helps anybody that takes it just becareful not to take to much incase you are driving or whatever...take care and I HOPE EVERYBODY HAS A HAPPY HEALTHY NEW YEAR!

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19

Google Lyrica and get the research that was done in Germany and Great Britain. Lyrica was proven to not help many people. I traced it after United Healthcare/ Optum "suggested" it instead of Lidercain pain patches.

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18

It is now a couple of months since the above post. I tried Lyrica again and have, for whatever reason, not had the side effects I had initially. I'm taking 100 mgs. BID combined with 20 mgs. Imipramine (Tofranil) in addition to my 4 mgs. Dilaudid QID I've always been on. The Imipramine, in addition to helping me enormously in the sleep dept., also helps with pain. After about two weeks, the addition of the Lyrica and Imipramine have reduced my pain to virtually zero! The Dilaudid alone never, ever did that. I've been unable to travel for four years because of pain, but now it looks like there is light at the end of the tunnel. It is odd not feeling pain that I am reluctant to call myself cured. Follow-up reports in the future. May you all find a resolution to your own suffering.

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17

I was just prescribed this today also, 75 mgs 2xaday and it worked immediately with my fibromyalgia pain. I don't mind the side affects if it helps with the pain

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16

Does anyone else (with Fibro) have near fainting moments sometimes when moving around?

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15

I have to say I'm really surprised you've had such strong side effects on such a low dose. I just started taking 100 mgs. BID yesterday. I fell asleep two hours afterwards on both doses and stayed asleep for nearly five hours. But today I took my first 100 mg. dose and the sleepiness effect was much milder. There is no noticeable pain relief, but I have endured the most disruptive sleep patterns for eight years. After my evening dose of Lyrica, I slept so well and feel better and more rested than I have in ages. I will report back here after I've been on it for a few weeks. My pain is closing in on four years with my taking four mgs. of Dilaudid QID. It has been pretty effective. But I had a colonoscopy five weeks ago and it aggravated my groin pain significantly which is why I'm adding Lyrica to my long list of meds.

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14

Yes. I suffered with what I now know is Fibro, but for 11 years, I had all types of cervical therapy plus micro neuro surgery to remove bone spurs and do a Foramenotomy. I came out of it with mild nerve damage from where the surgeon had to shift nerves aside to reach the bone spurs. When the pain persisted, I tried an epidural at T2 but during the procedure, I received a nerve shock down my legs and into my feet leaving me with nerve burning and heavy feelings in my legs and feet. And I had an awful adverse reaction to what the doctor injected. I had to lay around with ice for 5 weeks. When pain persisted in my neck and was also all over my body, doctors agreed, three years ago, that I had FMS and a Rheumatologist put me on Lyrica 75 msg three times a day. I feel like a war site. The first 20 minutes after I take each dose, the nerves in my neck scream at me before they settle down and I feel 70% pain relief. It's worth it! The main thing I am struggling with is that Lyrica slows time it takes food to get through my GI tract, so I have very hard stools and my muscles do not contract to help me pass them. I'm really in a rock and hard place, oops no pun intended ??. I'm taking a stool softener from a supplement store, ground chia seed for an insoluble fiber and a soluble fiber (but not everyday and with water but I need to drink more water) but each pm I mix Magnesium Citrate powder and vitamin c powder with water. The problem constipation still persists. I stay awake from stimulant laxatives because the colon gets hooked on them and they can eventually damage the nerves. When I tried Linzess, it caused Fibromyalgia nerve pain all over and no relief of my C. I read that Linzess reacts with Lyrica so I'm sure that is the reason. Plus I have allergy to gluten and some other foods (went many years undiagnosed so probably did damage to my small GI tract). Does anyone have any suggestions for me about constipation with Lyrica?

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13

Susan, 75 mg is not strong enough to help your pain,most doctors tell you to take stronger dose the next week if you don't have any improvement in your pain level
i used to take 75 mg twice day for nerve pain, i have nerve damage in my upper spine, so i have alot of pain.
I then went to 150 twice a day the next week!
Now its been 9 months, i just started taking 200 mg .
hope this helps you.twice a day.

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