Grapefruit Juice And Opioids (Page 2) (Top voted first)

So I just took my dose of liquid methadone and drank 3 cups of Grapefruit juice. A couple hrs later I pretty much blacked out on and off for a few hours. Has anyone else have this happen to them? Also I'm about to take my daily 60- 80mgs of oxymorphone ER. If I drink another couple cups of Grapefruit juice is that gonna happen to me again or does it only pertain to Methadone? Any and all info is appreciated thank you

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You're all mostly daft. Only white grapefruit juice nonconcentrated has the enzyme to change mainly benzo potentiation.

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Re: GmanzA1day (# 25)

Where did you get that idea from? Please share an article stating as much. This is what the FDA says on it:

https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix

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Re: cliff j (# 11)

Sorry, I may be naive because I've been on methadone 51 years but can someone explain to me why grapefruit juice does that? I'll be 71 and not looking to get messed up. On monthlies and take 120 ml a day as prescribed.

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It's guys like you Rawdog that are ruining pain management for the rest of us. You should not be taking any drugs if you do not know how to read or ask your doctor a simple question.

Grapefruit influences the activity of an enzyme in the liver that can increase the potency of the methadone.

Stay in your lane bro... quit trying to be cute... we can spot your kind easily here!!

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Re: House Jr (# 15)

Says house Jr. the drug addict from the show. Cute name. No wounder we have a problem getting meds, cause people like you!!

See, anyone can say it, doesn't mean it's true. Back off.

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Re: Cher (# 13)

And NO my pharmacy DID NOT mention this so I DID NOT disregard that. So yeah there's THAT!!
Thanx anyways

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Re: cliff j (# 11)

How many times are you gonna say Grapefruit juice!!?? STFU, and after that experience I hardly drink any anymore but get off my back psyco!! I lived and learned thanx anyways

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