Grapefruit Juice And Opioids (Top voted first)

So I just took my dose of liquid methadone and drank 3 cups of Grapefruit juice. A couple hrs later I pretty much blacked out on and off for a few hours. Has anyone else have this happen to them? Also I'm about to take my daily 60- 80mgs of oxymorphone ER. If I drink another couple cups of Grapefruit juice is that gonna happen to me again or does it only pertain to Methadone? Any and all info is appreciated thank you

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Rawdog I hope you are not trying to get f***ed up off your meds bro? Just saying bcuz that's what part of the problem that we have now and why the public have such a negative perception of methadone patients.They see some of us nodding off on the streets and in public places and think it's the methadone that has the person like that but it's the other drugs that were taken with the methadone that has a person looking all f***ed up and I don't think it's fair to the people who are on methadone and not using other drugs they are not supposed to be using while on methadone. Just my opinion Rawdog.

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I don’t know about methadone, but there are plenty of meds that you aren’t supposed to take with grapefruit juice. CBD oil does the same thing as the grapefruit juice, so don’t take CBD oil orally with medication you shouldn’t take with grapefruit juice.

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This is easy. STOP DRINKING GRAPEFRUIT JUICE!! At all. None. Why would you drink something that MAY not mix well with your meds? Just stop drinking grapefruit juice. There are literally dozens of other choices besides grapefruit juice (or orange juice, etc.)

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Has your pharmacy not explained to you that grapefruit juice interferes with many medications? Makes them ineffective! Why would you disregard this information?

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You are an accident waiting to happen Raw Dog!! People like you are why real patients are having such a hard time getting their meds. You think you are cute drinking 3 cups of grapefruit juice?? Wake up dude before you kill yourself or someone else!!

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Re: House Jr (# 3)

EXCUSE ME HOUSE JR. AS YOUR NAME IMPLY'S DR. HOUSE WAS A SHOW ABOUT A DRUGGIE DOCTOR. IT'S PEOPLE LIKE YOU WHO ARE GIVING DOCTOR'S A BAD NAME!! NOW YOU SEE HOW STUPID THAT SOUNDS. IT'S STILL ONLY HALF AS STUPID AS WHAT YOU SAID TO ME!!!!

I was simply asking if Grapefruit juice was only directed towards Methadone or all opioids? Not that I was trying to get all messed up, it was kind of scary and if this helps people become more aware about the dangers of Grapefruit juice then I'm a happy camper. So please stop trying to make me look like I'm part of this fake opioid epidemic (we all know it's mostly the IV junkie or the heroin and now Fentanyl users) that are making getting my pills so much harder. So go bark up another tree.

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Re: Rawdog (# 12)

Listen up. I repeated grapefruit juice because evidently you cannot comprehend to not do anything that makes you sick. A sane person would never have done what you did in the first place. I replied without insults to you the first time but not anymore.

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Re: Rawdog (# 9)
Anyone on this thread could tell by your rude and disjointed posts that you have no brain. And they would not need an MRI to "find nothing".

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Re: Rawdog (# 9)

That's great that you found some relief, especially from a walk in clinic! Cool deal. I've had cluster headaches for too many years to count, but finally found some relief from a bp med.. Crazy how we find our help in odd places sometimes.

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Re: Oshan (# 4)

I have Diclofenac Sodium in pill form and topical gel, both used for back pain. Is there a big difference between D. Sodium and D. Potassium that you use? If not you might want to look into that cause it's pretty cheap, $3.40 is what I pay for each one. Good luck.

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Re: Rawdog (# 5)

Your response was pretty funny, but yeah, grapefruit juice can be some powerful stuff.. Be careful, that's all..

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Re: Rawdog (# 5)

So you’re saying drinking 6 glasses of grapefruit in one day is just what you do? I doubt it man.

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Grapefruit juice is a big no no for Methadone and other Opoids. I was on the high dose Methadone program in Sweden for years. During the 1st 3 months all of us had to go to the clinic and submit a urine specimen in front of the women workers (one faces you through a hole in the wall at the bowl level and another stands next to you). Everyday a new expert would give an hour long lecture. One guy came to tell us what food to avoid. Hamburger buns with seeds can leave a positive response for morphine as they send them to labs. Grapefruit juice apparently is different in it's make up to nearly all other fruits. It's very acidic and Opoids are strong alkalines. The grapefruit juice stops the Methadone working causing adverse effects. Partly abstinence. So drinking a litre of my favourite juice is history. And has been since 1984.

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I am really skeptical that you are actually taking 80mg of Oxymorphone and taking 110mg of Methadone....There's no doctor that would get away with prescribing you this amount of medication.

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The medication to treat my migraine headaches is down to one. Diclofenac Potassium has worked like a charm for 30 years but for some reason went off the market. I called all the major prescription houses but found none.Now enter Anjovy. It is extremely expensive 800.00 per month retail. If your insurance company denies your prior authorization AJOVY will absorb the cost and give it to you for nothing.And it works.on the 2ntr Humanna approved my prior authorization. I was so excited! However, now that I’m on insurance it only costs 302.00 dollars.a month. I just can’t afford it. Now I have to live with nothing. Does anyone have ant ideas on Anjovy? I’ve had migranes for 30 years or Dioclofinic Potassium have any ideas . Please.

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Re: Oshan (# 4)

Hey, give me some info on dosage that you were on with Diclofenac Potassium, ie. pill form,injections, etc. I've never heard of Ajovy, but if you want to share that info, I'll help you look at options. There's a small thread on here, not much info, but give it a try, I'll paste it up here.. Migraines suck, and losing the meds that worked for you for so long sucks even more.. Maybe we can find you some help.

Anjovy Needs, Please Help My Migraines
3 Replies Updated July 29, 2019

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Re: TnJack175 (# 8)

I take Sumatripitan for my migraine and I have tryed quite a few other meds none worked like this. I call it my life saver cause without them I'd be screwed missing work and enjoying life. Just a side note my new primary doc was surprised that this med worked for me..and the weird thing is a wslj in clinic I went to actually gave me this med and found out that way(thank god) I've been having migraines since I was 13 had a MRI done on my brain but no findings. I again had one done 6 months ago and again no findings so I have no idea why I suffer half a month with migraines. I couldn't imagine getting my meds taken away after finally finding the one that works. Good luck hope this helps.

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Re: Oshan (# 4)

Your probably taking the 50mg diclofenac. The pharmacy I work at has been out of this dose. Ask your dr or ask your pharmacy to contact your dr to see if they can change it to either the diclofenac er 50mg or the er 75mg. Same med but they may just have you take less of it.

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Re: Chris (# 22)

I would never prescribe my patients Methadone and Oxymorphone for pain....In my professional opinion it's way too high of a dose number 1 and number 2 I am pretty liberal with prescribing pain medicine....I would never prescribe these 2 drugs together simply because they both depress the respiratory system way too much when taken together or even separate. There are other long-acting and short-acting opiates that work better together than this combination......

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Re: Cher (# 13)

Exactly ?? right......Also let me just say........Even when I prescribe legitimate doses of pain medicine to people with legitimate pain Acute and Chronic pain.....The pharmacy is always calling me or texting me questions.....Like are you sure this patient is having severe enough pain to prescribe them Dilaudid or Oxycodone.......So it's beyond my comprehension for this guy to be getting extremely high doses of Methadone and Oxymorphone and no pharmacy or pharmacist has said no.......Absolutely not. Just saying ??

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