Glutethimide Is The Best Hypnotic

Sadly Glutethimide (Doriden) was discontinued by the last remaining manufacturer Halsey Drug (HD 550 on white round tablet) in late 1992. The DEA practically forced the FDA to make it a schedule ll drug with the ridiculously low quota of six grams. They were the best, especially with codeine ("Hits", "Cibas & codeine "). Yes they were abused but nothing like the opioid abuse epidemic of today. The last countries that used them were Hungary, Romania and Bulgaria. Doriden inducted a liver enzyme CYPD26 if I recall correctly, that made the codeine convert to morphine 80 to 90% instead of the usual 10-15%. It was very long lasting and effective. Finding any Doriden would be like finding the holy grail.

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Yes, Glutethimide combined with codeine was big in my part of the country. It produced an intense long lasting euphoria that is unequaled to this day. I'm in the NJ/NY Metro area and they were very popular like I said. It really is too bad that they were discontinued in '92-'93.

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