Extreme Fatique, Joint Pain, Muscle Weakness With Eliquis For Afib
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I was having extreme fatigue, joint pain, muscle weakness after starting Eliquis and started to having black stool with nausea and abdominal pain. I gradually reduced the dose until no longer taking Eliquis nor ever will. It really put a fear in me. Asprin works for me via my AFIB. I can tell if my blood is too thick when my heart is working hard to pump the blood out of my heart. I feel much better when my heart is pumping normally when the blood is thinner. You sometimes have to insist to your doctor the side effects you are feeling, this is a fairly new medication. Anyone else have these side effects?

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109

I started Eliquis on Dec. 17, 2023 was put on because i have 100% Afib. On Christmas eve I started getting a severe pain on my left side (my back). I just shook it off thinking my pants were to tight. Christmas day the pain got worse. then I noticed my urine was getting darker. Then my urine got real dark. I started noticing I was so tired and weak that I couldn't get out of bed, didn't have a bowel movement since starting the Eliquis, then the blood started in my urine. I am now starting to get dizzy, feeling awful, finally I said that's it, I go to see my PA because my Cariologist doesn't respond to my calls, and she says that there is so much blood in my urine, so she put me on an antibiotic and tells me if I feel worse to take myself to the hospital. Now it is New Years eve and I am at the hospital. They do a cat scan and say they don't see anything, they do blood work and that seems alright, they do a urine analysis and tell me that I need a Urologist. The ER Doctor asks me if I am taking any new meds and I tell him Eliquis and he says "Oh", he thinks this could be my problem. I leave the hospital and I take myself off the Eliquis. After a couple of days I see that the blood in my urine is getting better and the pain in my back is going away and the weakness and tiredness is going away. I go to the Urologist and he does a test on me to make sure that I have no cancer in my bladder which comes back negative. He also thinks this could be the Eliquis. So I told him I am staying off of it. I now have an appointment to see a new Cardiologist. I don't think I will be going on any blood thinners anymore. I am scared about having a stroke but I don't think that I can live with all the side effects. I am going to look into natural ways to thin my blood.

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108

I was placed on eliquis for pulmonary embolism, I too am having extreme fatigue to the the point I fall asleep sitting up and extreme leg muscle pain

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107

Wow, glad I am not alone. I too have fatigue, weight gain, but the dizziness is the worst, scary. I don't want to have a stroke so I take it but have been sporadic. I have an appointment for an ablation consultation next week and I hope and pray it works.

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106

Anyone else have back pain after taking Eliquis.Went off it for a couple of days due to a procedure and the back pain disappeared. Back on it again and back pain and inflammation under the ribs started again. I have persistent Afib,cardioversion did not last waiting to see electrophysiology.

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105

Re: Bobbir (# 93) Expand Referenced Message

I had a similar situation, I traveled to Europe and had been taking Metropolo and aspirin for 8 years, I had a stroke while on a cruise ship in the Baltic sea. I was in the hospital in Helsinki. Pradaxa gave me severe heart burn. So I am on Eliquis now. I do get dizzy but feel alright. I exercise and feel pretty good. But don't tell my Doctor or he will get mad, I am taking half the dose. But I take Aleve for pain so I think it balances out.

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104

anemia!!!!!!! don't overlook it, iron and b12 could help a great deal

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103

2 x 5mg, after a month my legs are very weak. I was fit and strong before an injury caused dvt. I did not want to take pharma but also didn't want to die, going the natural route. Hope I can clear the poison soon. eliquis = poison

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102

Re: BeccaB (# 96) Expand Referenced Message

Ditto to all you said... Was about to get an MRI & decided to do some research and WOW was I surprised... Had similar issue with hips when on Crestor years ago... Stopped taking pain subsided. Have to d/c this Med. Has your pain subsided yet???

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101

Re: Nana (# 95) Expand Referenced Message

Look into natural blood thinners like Tumeric...There are also many others...
I am having many pain issues also with Eliquis.

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100

Re: Hope (# 94) Expand Referenced Message

Look into a Natural remedy called “Mastic Gum”...
For me it’s a Miracle for my belly.

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99

Re: Lexie (# 89) Expand Referenced Message

Lexie What is INR???

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98

Re: Lexie (# 84) Expand Referenced Message

Look into Natural remedies...Tumeric comes up as Number one...there are many more

Developed small clot lung after 2 week stay in hospital via Covid & Bacterial Pneumonia...
Increased my Eliquis to 5mg 2x day and have Extreme pain shoulder...arms neck...starting in back...
I need to resume to Aspirin and Natural remedies...
I too have gained 20+ pounds...Some due to Steroids but have been off for awhile...Think it’s the Eliquis...Dietary not helping...Can’t loose this weight.

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97

I was on Eliquis from July of 2016 to July of 2021.
I had many problems. March 4 I had aWatchman filter put in snd had to take Eliquis till end of June. I feel so much better. I am in permanent AFIB and take diltiazem 30m every 6 hrs. Had problems with constipation. Dr gave me 400m of magnesium. I also take one baby aspirin a day. I take iron and folic acid every day that helps me with the fatigue also B12.

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96

Yes, I also have severe muscle and joint pain, especially in my arms shoulders neck. I also have a general feeling of not being well, and fatigue. My symptoms are worse in the morning, if I don't take acetaminophen I can't function. Before taking Eliquis I was strong, active felt great, now my quality of life has dwindled to about a 3. I decided I would take my chances with my afib and start a low dose of aspirin and other natural supplements that will aid in better heart health. So I have only recently weaned myself off of Eliquis, it has been one week and still have the pain. However the general feeling of not being well has gone as well as the fatigue. I hope the pain will subside in a couple of weeks.

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95

My husband has been taking Eliquis 2.5 MG 2x a day for approx 6 weeks. Prior to that 1 81 mg aspirin. Has developed severe arm and leg weakness to the point of not being able to go up and down steps or get up from chair/commode. We have reduced to 2.5 1x for last 2 days and are going to discontinue it all together in next day or so. Also has red blotches all over his legs and is extremely fatigued. No more.

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94

I am 82 yrs old have had AFIB for 4 yrs since I had my hip replaced. Had a small stroke 6 months after hip replacement. No after effects of stroke. Dr put me on Eliquis. I have extreme fatigue weaknesss and dizziness, Went to ER and they found nothing, I could sleep all the time. Started research and looked at side effects. I started taking Vitamin b-12 and Iron. If I take them in the morning I feel much better. The Eliquis has affected my stomach and I get sick when I eat. I go to the Gastrointerologist next week. Hope he can find the answer.

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93

I was taking aspirin & metroporlo for 7 years but I had a stroke on vacation. I was on vacation when it happened so went on pradaxa for 3 weeks, but the had severe heart burn. I am taking Eliquis now & I felt weird at first but I stayed on it & am doing fine now. I am 67 & so far si good.

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92

I have had all of the above problems with eliquis. I was in the Hospital with Blood Clots in my lungs and the Dr. put me on Eliquis. I had Blood Clots a few years ago and my DR, put me on another drug and I had to have my blood checked every Month, but I did Fine on the other drug. The Dr that put me on the other drug has since retired (all the GOOD Dr's are retiring) I feel pain and Leg and joint pain and muscle pain and I am having trouble walking. I am hoping the DR. will put me on something else soon .

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91

We Eliquis users need another pain killer besides Tylenol which is next to useless.

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90

After about 1 month of starting 5 mg twice daily Eliquis I have developed debilitating joint pain in my back, neck, knees, elbows, wrists and ankles. I had been walking miles a day and doing light aerobic classes, but can no longer do either. I now find it nearly impossible to get up from a sitting position, and have a hard time getting on or off the toilet. These symptoms are all new since I started taking Eliquis.

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