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Depakote, Kepra, & Topamax

Updated September 30, 2023
Comments Submitted Says:
Thu, February 9, 2006

What are the side effects of a combination of all three medicines for a seizure disorder? Have been on the Depakote and Topamax for years with the Kepra only recently added for partial seizures. I noticed that my hair is now thinning dramatically and I'm now suffering from insomnia! I'm thinking it may have something to do with the addition of the Kepra. Am I correct? Is there a solution for this problem? Has anyone else ever come across this problem or complaint? I will, of course, consult my neurologist before doing anything. Just wanted to know what you thoughts.

1 Reply

1
VerFree Says:
Sat, September 30, 2023

The basic side effect profile remains the same, and the FDA lists it as including things like nausea, dizziness, drowsiness, sedation, mood changes, weight changes, and the hair loss that you mentioned, however, they may be more severe, and intense, when you are taking multiple medications like this.

Ref: Anticonvulsant Information

Have you informed your doctor of the insomnia? They may know of a way to mitigate it, or they may need to adjust your dosage.

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