Contrave And Dental Procedure

I haven't been on Contravene for months as I lost my 35 pounds and maintained it. During the holidays I picked up some weight. Just took two today and forgot I am having a root canal in 30 hours. Should I be okay? Afraid it will block the pain shots he gives me to do the work on me.

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@Dental Patient,

Is your dentist also aware that you're taking any prescriptions? If not, I think it would be important to inform them if not but for your own safety; especially if something they administer has a possibility of interacting.

Umm.edu's drug interaction checker mentions that Contrave may decrease the effectiveness of opioid medication.

According to NIH.gov, "the average elimination half-life of Naltrexone (one of the active ingredients in Contrave) is four hours, and the mean elimination half-life of it's metabolite 6-β-naltrexol is 13 hours" - So 30 hours later my guess is that the greater part of Naltrexone will have run its course, but it's metabolite may still be lingering around.

Given this information, it's hard to say how much of an impact Naltrexone's metabolite might have when it comes to drug interactions. But if you were to play it safe and reschedule for a couple days later I seriously doubt there would be any interference. That's why I think it's probably best to get your dentist's opinion as well.

Hope this helps!

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