Darin Says:
Can Tramadol Cause A False Positive For Methadone On A Urine Drug Screen?
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Tracy Says:
I was taken to the ER by ambulance this week because I had a seizure and fell, hitting my head on concrete & was unconscious for about 10 min. Luckily I was in our parking lot & someone witnessed the whole event, so I got help right away! When I came to I had no idea where I was (I thought I was in our living room even tho I was actually laying outside in 4in of fresh snow & it was raining). In the ER they told me my urine was positive for methadone & asked me where I got the pill from, told me this is why I had a seizure & could go home. I was speechless!!! Talk about shocked! I've never seen methodone let alone taken it & I've never had a seizure before so I was scared by this event & wanted them to figure out what really caused it! I asked them to test another sample while I was still there (thought they mixed up samples or something), again was positive for methodone. My daily meds are Tramadol, Yasmin, Clonazepam, Ibuprofen & I had taken 2 of my Percocet for pain the day before, but don't take that everyday. Could any of these have caused the false-positive on the urine test? I am really upset about this-I don't want to have that in my medical record because it's inaccurate & I don't want my doc to become suspiscious of me in any way, plus I work for my dr's office. I also want to know what caused it so I don't have problems with future pre-employment tests. I called the ER the next day to asked them to send my urine for gas chromatography, but I'm not sure whether they'll do this since they don't feel this is medically necessary even if the result was inaccurate. The ER doc thinks it may have been the tramadol that caused the false positive because tramadol & methadone one are both synthetic opiates & I take a high dose: I've taken 400mg daily x 4 years. I would greatly appreciate any insight anyone could provide me about this false positive!!! Thank you!
50 Replies (3 Pages)
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Re: Ricky (# 3) 
I had a seizure due to tramadol and they accused me of being on methadone too .trying to get it off my record at charlotte Presbyterian.
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Rick Says:
Re: Verwon (# 2)
You have no idea what you're talking about in regards to oxycodone and methadone, completely separate chemical structure and metabolites.
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MAA Says:
It will come as methadone. order a 7 panel test, and use it. I ordered my test on Amazon for under $10. I promise I'm correct
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Wicked witch Says:
Will tramadol hydrochloride 50 mg come back positive for methadone and other narcotics on a 7 panel urine drug test?
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MAA Says:
Trimidol test positive for methodidone. Not the percacets. Percacets will test positive for opiates. I'm on trimidol no because I had a tummy tuck. I'm going back to work so I've been testing myself to make sure I go back with a clean system. Yesterday I test my urine and it said positive for methodidone. I've never used Methodidone in my life. It's the trimidol, trust me.
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Lorianne Says:
I take two 50mg tramadol daily. My doctor did an annual drug test and I tested negative for tramadol but positive for methadone. How is that possible?
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Blake Says:
How do I get that more extensive test u were referencing if I have a false positive
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Meech Says:
100% it was the Tramadol. Last Saturday i took a high dose of my tramadol about 400mg. While i was driving on the highway with my family. I blacked out and had a full blown seizure. I woke up in the ambulance being told i had a siezure i swear i thought i was dreaming. When i got to emergency room the doctor came in and asked what kind of medication i was on. I told them only Hydromorphone and Trammadol. The doctor said that she was sure it was the Trammadol that caused the seizure. She said Trammadol causes you to be highly suseptable to seizures. i never had a seizure before in my life. After the initial visit she ordered a blood test. Shortly after the doctor came back to see me and told me i tested positive for Methadone. I looked at her like she was crazy. I don't even know what Methadone looks like. I couldn't believe what she was saying. After she left room me and my family started doing some research. What we found from many credible sources was if you are taking Trammadol in high dosages you can test positive for Methadone. Shorty after i saw the doctor again and shoed her the findings. Said she was not aware of that and would look more into it.
So long story short it was 100% the Trammadol. Our story sounds very simmilar.
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JeffPA Says:
The most common cause of lab error is switched samples. That would be a higher risk than cross reactivity. Medical staff are aware of this and that was the reason for retesting. Labs take extra precautions to avoid switched samples, but you have to take the sample out of the labeled container at some point and these things are done in batches of multiple samples. It is just a reality.
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Cheyenne Says:
Yes it will, show as Methadone and an antidepressant, but everybody is different so it depends on what drug test is being used and what exactly is being tested for!
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Suzii Says:
I failed a test thru probation for methadone and I take tramadol. They sent it to the lab and it came back negative. So yes tramadol shows up as methadone.
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Cherry Blossom Says:
Did you take any OTC or cold meds? Sometimes those cam cause a false positive. I am on methadone as well and have had two (one saliva and one urine) false positives on drug screens. One was for benzos. I haven't taken any benzos since I started the methadone program over a yr ago. I was on .5 mg xanex twice daily but weaned off. That was in Jan of 2015. And that was a urine test. Then the saliva test was negative for methadone even though I haven't missed a dose. And it was positive for oxycodone, which I didn't take. Since those are the only dirty tests I've had in over a year, my nurses and counselors believe me. I have no idea what caused it.
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Melissa Says:
I am on Trazadone Methadone Xanax and Cymbalta. 2 I took a urine for DC&P it came up positive for PCP. They had me retake the test the next day and set my urine to the lab. The retakes came back negative and so did the labs. What meds that I take cause this!
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Blessed Says:
Yes you can.. I had two test come back postive for methadone while on tramadol. I had my urine sent out and analyzedo by lab core and it came back negative. Do not let anyone falsely accuse you.
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Dawn Says:
Tramadol does show a positive and negative in urine it happened to me and I called my pharmacy and he said it can
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MClarky Says:
I recently took a drug test at home because i have been abstaining from smoking pot, 25 days and still faint line but thats not the problem. I have been taking tramadol for a week because of pain and i am utterly gobsmacked at reading the results of the test. I have tested a big positive for methadone wtf i would just like to make one aware of this just incase you believe other wise. I have pics but dont know how to upload them
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JEFFPA Says:
Dr. John,
I am doing personal research for a friend who is testing positive for several opiates he has not taken. His security clearance is on the line and I need data. I have the credentials and letters to understand, but not the mobility to get to a professional library. Can you give me a few references on the false positives for tramadol such as you listed in post #16? I would give you an email, but this is too public a forum. TIA
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Dr John Says:
Please READ my post 16 it will answer a lot of your questions.
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sheshesd Says:
Yes, it does. I've never taken recreational, illegal, drugs in my life and Ultram has shown up in my urine test as Methadone.
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