Bupropion Xl By Cipla Pharmaceuticals (Page 2)
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My pharmacy has been giving me refills of the generic bupropion for my last two refills that are manufactured by CIPLA. The pill is oblong and has the number 13 on one side and what appears to be a capital I on the other side. I do not feel that this generic is doing much for me. I have researched this manufacture they are located in India. Approximately 45% of the medications that are sold in the United States are manufactured in foreign countries. I am going to call my pharmacy to see if they can get one of the generics that were previously dispensed to me. The buyers for drugs at pharmacies look to find lower priced drugs, which I understand.

I have been taking Wellbutrin XL 150 mg three tablets daily for about eight years including the generic form. This medication helped my severe depression. I have tried many other families of antidepressant medications that did not work or caused side effects. The cost for the brand Wellbutrin XL continued to increase because of big Pharma greed (a discussion for another time). Eventually I had to go to the generic Wellbutrin because of the cost and my insurance would not pay for brand or my copay was too much.

When I could no longer work because of my Multiple Sclerosis and another incurable gene mutation condition I eventually received Medicare. I continued to take generic bupropion XL because I had no choice. Various generics of this medication have been dispensed to me for a number of years. The generics have never been a good as the brand Wellbutrin. For those of you that may not be aware a study was done that proved there was a difference between the brand and the generic. The main factor is that generic Wellbutrin XL rises quickly in your bloodstream then drops. The brand Wellbutrin rises up in your blood stream then goes down over a number of hours.

Perhaps for some people the generic form of Wellbutrin works okay for them. In generic medications different fillers are used and the percentage of the main ingredient can be less or higher on either side of the main ingredient. I know a pharmacist that explained this to me that confirmed my suspicions. I take other medications that are generic that seem to do okay. Nevertheless, I firmly believe that certain medications such as antidepressants, seizure medications to include some others should not be propped up as being a bioequivalent.

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OMG I have been on a generic, zydus, for years with little to no issues. Since January I have gained a significant amount of weight, am tired, depressed and have skin issues. I vaguely recalled that walgreens said they were switching manufacturers and sure enough it was in January to actavis. the only thing I can find locally is the Par....anyone have any positive feedback on that one?

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I have taken Bupropion HCL XL 300 mg for several yrs. I recently refilled my prescription and got them mfg by a company called Cipla. I have been taking for only a few days but I am severely depressed, cant function, crying all the time and suicidal thoughts. CVS told me this is the only manufacturer that they are buying now. Tomorrow I will shop for another pharmacist that buys from Par.

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Wow, I started on the Cipla brand of 300/150s last year and it coincides with IBS symptoms that I have never had before. So now I am on a med for that. Is there a correlation. I have taken Welbutrin for 15 years and have taken the Teva generics and the brand and never had side effects, now I am jittery and have intestinal difficulties. Did not get the correlation before I read all of this.

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After being on generic buproprion 300 mg xl by Sandoz for many years my pharmacy dispensed Actavis generic. I didn't want to take it, but had run out and that's all they had. What a mistake. It took a few days for me to feel the difference, then I was energetic and active in the am, afternoon and evening were hellish depression, in bed with covers over my head. That continued until the last week of the supply when my symptoms shifted to a high that I had never had before. I was singing loudly and wound up tight, plus so active. I have fibromyalgia and and spinal stenosis. I live with chronic pain and severe fatigue, sleeping far too much. I was thrilled to have some energy and be able to get stuff done, but knew that the Actavis was messing me up when the last two days in it I started to hear thing, like voices from a radio or tv, but they weren't turned on. Now I have a new supply by Par from a different pharmacy. They told me they had Mylan generic, but when I got there nope it was Par. Its very disturbiby that the pharmacies are calling the shots on our generics. Every pharmacy I called said they can only get what their warehouse has. One offered to order me the Mylan but cautioned me they couldn't promise it every month. WTF this is our brain they are messing with ! I totally agree that antidepressants and seizure generic meds should face a more rigorous approval process. I'm at a loss as to how I can obtain the generics my body is used to having. BTW no one could order the Sandoz, not available. Most all pharmacies sticking the three cheapest generics, Actavis, Cipla and Impact ? I also take Pristiq 50mg and cymbals and still suffer major depression.

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FYI --on my bottle it says Manufacturer: CIPLA, USA Inc. Not sure if that means it is manufactured in the USA.

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GO to pillbox.nlm.nih.gov as this link will ask you for the description/or medication name. I put in the MEDICATION NAME ONLY on the right side of the "form". I uncheck the "do not search for repackaged or relabelled" choice. THEN HIT SEARCH... you will get a lot of pictures of particular medications in that class, i.e., Wellbutrin is Bupropion Hydrochloride. I look up and down the page for the 150/300 XL as this is the one that I take. When I find the particular dose, I hit the "show more information" button to see fillers and such.

THE IMPORTANT THING TO CHECK IS THE DRUG LABEL INFORMATION. THIS CHOICE WILL BRING UP "LABELS" FROM THE MAKER/DISTRIBUTOR/MANUFACTURER. I will no longer get any drugs from China or India or a third world manufacturer, (other than Germany or strict control countries). If the "label" does not say "manufactured in US or Canada", then it is made god knows where and distributed in the US by the company shown on the label. COMPANIES HAVE DRUGS MADE IN FOREIGN COUNTRIES AND DISTRIBUTE IN THE US., however, I PERSONALLY LOVE APOTEX IN CANADA., AND MYLAN-LOOSE PILLS/PREPAK. Cipla, I believe is made in Peurto Rico? Not sure.

I signed up for notifications at FDA.GOV regarding drug recalls. THE FDA DID A 3 YEAR STUDY AND DECIDED TO LET FOREIGN DRUG MANUFACTURERS POLICE THEMSELVES as to the quality controls of their medicines. Well, I know the FDA cannot be everywhere and cannot "search the quality" of all drugs entering the US, therefore, BE VIGILANT FOR YOUR OWN SAKE. When Walgreens would not fill an RX for my daughter for sertraline with a US/canadian company, I went too a local pharmacy and they had no problem "special ordering" the med for me. I PUT IT ON MY RECORDS AT WALGREENS THAT I WANT NO FOREIGN MANUFACTURED DRUGS OTHER THAN USA OR CANADA, I DO GET SPECIAL ORDERED MEDS AT WALGREENS, BUT, THEY WILL/CANNOT ORDER FOR EVERYTHING. I WILL GO SOMEWHERE ELSE IF I CANNOT GET DECENT MEDS AT WALGREENS. Good Luck to You! Hope this helps!

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AMEN TO THAT!!!! We are paying top rate prices for 2nd & 3rd & 4th rate service

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So sorry to hear you are dealing with this. I have had success with the bupropion XL generic by Par pharmacy. I was switched the Cipla for a couple of months (without my knowledge) and I had terrible gastrointestinal distress. Depending on where you fill your prescription, you can request a different supplier. I use CVS and request the Par bupropion XL. Good luck!

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it is not for weight loss, although some do lose weight on it. Further, it tends to not cause the weight gain many experience on SSRIs.
It absolutely can raise blood pressure. Experiencing this now but I've done pretty well on WB so working with PCP & Pdoc to manage the bp with a bp med.

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This isn't a weight loss medication. It's for people who suffer from depression.

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Do you all honestly think the workers in India have a salary equivalent to the prices we pay for meds?? I DONT THINK SO!! SOMEONE IS BANKING BIG BUCKS

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I started on this a couple of months ago and everyone said I need to get off of it because it is not helping me loose weight. I'm getting so upset on it I literally pull my hair out. I snap at everyone and everything. Does anyone know if it raises your heart rate and blood pressure? I never had that issue. Blood pressure has always been so low for both doctors and they'd jokingly ask "are you alive"?

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Walgreen special ordered the Par brand for me, the Actavis gave me bad side effects that I never experienced with any of the other generic brands.

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Found bup hcl lx @ Walmart PAR mfg! Is this detailed enough?

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I just called my local HEB (if you have those in your area) and they said they still carry Phar Pharmaceutical. I've been on Cipla for 2 data and feel ok but I'd like to know if anything goes wrong then I can go back to Phar.

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I was calling various pharms today looking for Sandoz or Mylan. Sandoz doesn't make a generic for the XL, only reg. and SR. Mylan only makes XL in 150s or 300 at qty 500. That said, an independent pharm was able to order Actavis (Teva is their generic arm). CVS said they could try but no guarantees. Walgreens same. One other private pharm had access to PAR. It was AHF (Aids Healthcare Foundation or AHF.org to search your area) in Ft. Lauderdale. With the indys, availability is contingent on their wholesale distributor.

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Re: bupropion hcl xl CIPLA mfg. CVS pharmacist said no more PAR mfg., their cost, I'm sure. Does anyone know another chain pharm that carries PAR? Happy to leave CVS far, far behind

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YES YES YES. The CIPLA sucks!!!! Big time. I feel like I'm going through withdrawals.

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I just started this brand of wellbutrin a few minutes ago. Also take ativan 2mg twice daily. I am a nervous wreck. All the pharmacist kept saying was information about seizures over and over. So what brand is better or should I wait and see if this one works

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Not only did Cipla's version of Wellbutrin do absolutely nothing for my depression, but it gave me headaches, severe bloating and uncontrollable gas. To make matters worse, I gained 5 pounds in 2 weeks. Needless to say I went off and currently looking for a pharmacy which carries a decent generic brand.thanks for nothing CVS and Cipla!

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