An 627 Round White Pill
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Has your doctor advised you to use them both?
Both medications can cause depression of the central nervous system, so a doctor has to take the dosages under careful consideration, when prescribing them together.
Therefore, they should never be used together, without a doctor's approval and supervision.
https://rxchat.com/wiki/Tramadol/
https://rxchat.com/wiki/Methadone/
It also means that this combination might not be appropriate for someone that suffers breathing problems, such as COPD, or a person that has liver problems.
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