Abuse Deterrent Xtampza Vs. Oxycontin (Page 2) (Top voted first)

Newly FDA approved Xtampza ER has a different abuse deterent additive than Oxycontin, however I have not tried it yet for effectiveness. I have taken Oxycontin over 10 years so I felt the huge difference when they began adding abuse additive to it. I am curious if anyone has info on this new med, how it works as compared to Oxycontin, or all info on it that may help me decide if I should switch? I always had excellent results with Oxycontin but when the abuse stuff was started it took so much away from effectiveness. Appreciate any info. Thanks.

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Re: Ktb (# 45)

Xtampza is oxycodone with a different delivery system. So if someone is allergic to oxycodone then this would not be the drug for them. Also the half life of oxycontin is 4.5 to 5 hours but that is only when half the drug is metabolized and it is at its peak. So it would take another 5 hours to be completely metabolized. That means that thus drug is a twice a day medication as the manufacturer and the physicians state. Now every body is different and some may get rid of the drug faster or slower than the average. I have seen it written for 3 times a day before but no more than that. From what I have heard and read about xtampza has about the same half life but seems to take effect quicker than the oxycontin and may stay around a little longer. Obviously, the main difference is that the oxycontin is a tablet that has to release slowly whereas the xtampza is a capsule with small abuse deterrent beads inside that release the medication in a small amount at a time. The beads are different sizes that metabolize at different times. I personally would prefer the xtampza delivery vs the oxycontin delivery but both are made for twice-daily dosing.

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Been on OxyContin for 18 years now. In the old day's I was getting 120 mg when they first came out! Then only 80 mg, then tamper proof in late 2009 which were no where near as good! Now this! Been on almost everything, Fentora which by the way was the best (GREAT) however, after 2.5 years at a cost of $5,000K for 121 doses per month, Busted Cross & Broken Shield declined to cover any longer. Their reason was that the pain wasn't derived from Cancer! This may help some people in FL with legit pain! BCBS of FL will cover OxyContin with prior auth. until 04/1/2018. That may give u more time to find another Provider. In addition, they will still cover Oxycodone with prior auth. Simply put, I will seek an alternative to Xtampza. I'm the only one that can say what helps me deal with my Handicap, not the insurance company or the Gov!

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Re: Darda (# 13)

Drink way more than the recommended amount of water when taking these and you'll find they work much better and faster.

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Hesitate to say it but I feel like you are typical of one of the abusers that makes it so hard for those of us who work with our doctors to figure out what will work for our situation. I would be curious to know where you get all of these pills that you are able to pop them like candy. Xtrampza er releases every 12 hours. Are you aware of that?

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Re: Markemark (# 4)

I hope you are right! I have to switch from Oxycontin er 30mg to whatever equivalents to Xtampza because of insurance. Also on oxycodone 15mg 4x a day. Hopefully I will not notice a difference or get more relief like you say! So tired of taking pills! But it’s the only way I can function. I’ve tried cutting down but if I do, I end up laid up because it’s just too painful to move.

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Re: Ktb (# 38)

Just saw something the other day about big pharma. I'll put it out there for the rest of you. Check it out please & spread the word!!!
They are "researching" (I can't even describe how frustrating to properly emphasize with these quotation marks) in Columbia. Yup.
They've paid, more specifically we've paid to get around FDA/DEA rules in the U.S.A. If they do it here, openly, they would be prosecuted & lose their monopolies to screw/abuse us legally.

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Part of the effectiveness of opioids is that they change your brains perception of pain so when they put something in it to change that aspect it isn't going to work as well. Opioids do not do anything for pain in the aspect of affecting the nerve or reducing inflammation. They work by working on the chemical receptors in your brain and changing how it deals with the pain signals coming into the brain. The euphoria you feel is part of that medication working. When it's reduced so is the effectiveness.

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Re: Markemark (# 4)

I tried xtampza 18mg for the ER aspect 2x daily for 1 month. I was taking 6 to 7 10 mg oxycodone for several years and I was becoming tolerant. I have a bad diagnosis of degenerative disc disease which I will need fusion from bottom of Cervical to tail bone I am going to be 47. The xtampza is the worst medication I have ever taken. It has 23 side effects to include back and muscle pain which makes no sense. I got no relief none whatsoever. I think the FDA rushed this to appease the judging public. My meds were changed to 20mg oxycontin ER 2x and 20 mg oxycodone for breakthrough pain. That is working. People who need these to just survive should not be judged or kept from what they need because the popular opinion of anyone who takes these meds is a junkie. I have almost taken my own life to relieve the pain. The psychological aspect of chronic pain is often overlooked unfortunately. Sorry I rambled. Xtampza is horrible and was created to make people who don't need them feel like they are doing something. That is BULL S***!!!

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Re: Markemark (# 4)

Good to hear as I have been on 20mg ext release plastic for ten years and just got prescribed Xtampza. From what I’ve read, the 20mg oxy ext release I’ve taken all these years, gets digested before all the medicine gets into your system but, with Xtampza, your supposed to get close to 100%. I’m looking forward to taking them and I’ll let everyone know how it goes!

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I thought the cottage cheese and ensure were making a difference with me. I just wasn't sure. I don't each much by mouth anymore so hard to get all the fat needed. I have been on OxyContin in past but problems with it sticking in throat. It was overall a better medication. Maybe they will get it right sooner or later. Thanks for your input!!

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Been on xtampza for several months. Was on 30mg oxycontin 2 a day before that with 5 mg of oxycodone up to 4 times a day for break through pain. I found the xtampza works fine for me. In fact I can make it through the 12 hours and was never able to do that with oxycontin.

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Re: Lynn (# 24)

12 hours! That's great. Is your Xtrampza er Rx equivalent to your previous Rx? I can never tell if mine's lasting the same from one day to the next. Some things I do one day I pay for it the next day or two at least. I'm trying to move around more but my muscles don't like it. When I hurt I just crawl in the bed and sleep. My pm suggested a Zumba class! He knows I'll never do it but he's trying. Just wants me to get my heartrate up and lose 'some' weight. Gotta help. Sorry I started talking about me. I ask everyone about what they take with the Xtrampza. How about you? Everyone has a different answer. Don't know if I'm doing it right. I'd appreciate your insight since you seem to have the formula right. Again, I'm really glad that you're doing well. Nobody likes to hurt. Thanks for letting me pick your brain! G'day!

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Re: Really agitadated right shoulder Oxycontin guy (# 39)

Ok I will be watching for it !!! Nothing surprises me anymore and yes we are constantly screwed over !

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Re: Retired Nurse helper PT to others (# 33)

I can understand your frustrations on how you're going to make the switch to Xtampza er especially since it's being forced on you starting on the first of the year. Just a really short explanation on how I got to this point. I was referred to a pain mgt. group to deal with opioid rx's. They started me out on 4 5mg pills a day. Progressed to 7.5. My primary said to ask about going on er to make sure I got the 4 pills in every day. They agreed. Started 13.5. Upped to 18. Sorry, I can't make anything short. What got me on this site was questioning what food and how much to take. Have learned a lot by just reading all these posts. The most helpful thing I've picked up is from Mr. Ryan on another group also on this site. Only way I know to tell you how to find his posts is to search Xtampza er at the top and scroll down to the left where it points you to 80+ posts and scroll till you find him. He goes into such detail on his story and what he has found that works for him. His trick is to set his alarm for 3:00 am, eats a bit, takes his pill, then goes back to sleep til 5:00 when he has to go to work. This gives his pill time to kick in. If you find his posts on the other group you'll get the rest of his story. If you can't find him, give me a shout and I'll try to get you there. Personally, I have my pill, snack and drink right next to my bed and follow what he does. Like you, I can't move first thing. One thing I will tell you, in case you don't know, is that Xtampza er does not have acetaminophen in it. I take some with my first dose of Xtampza. I think this kicks in pretty quickly so that might help. I wish I could tell you what magic would help. Read up on anything you can find on this site. You'll get a lot of ideas you never thought of and can explore on your own. I'm not the sharpest knife in the drawer so I have read over this stuff numerous times and am still learning. I encourage you to work with your prescriber until you get it worked out. Don't be afraid to talk to them. If you don't, they won't know that you need help. So much for keeping it short, huh? Hope you'll check back with your progress. Best of luck!

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Xtapza er 13.5 seemed about the same as OXy 10 er, but caused occasional nausea problems. Was increased to 18 mg and can't stop puking. Taking two OXy 10 at a time never did this. Also, did not seem to be equilivant, but slightly less. (Ymmv). Have been on OXy for over 20 years, both er and ir, and had two surgerys so far. More recomended.

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I was on 40mg of oxycontin , 3 times a day. I was switched to xtampza er 36. I like most see abuse deterrent and thought would be weak. WRONG! If you do not abuse or even if on oxycontin since 1996 this formulation is strong like the 1st ones to come out. Purdue is suing the makers for billions in fact for infringement. They are twice as efficient as the O.P.'s. There bio-availability is 89% on empty stomach as opposed to 67% in OP's. This is from an independent lab. Most insurances cover or will with p.a.

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Re: Kris (# 55)

I just started xstampa 27mg. 4 per day. I was on oxycotin 60mg 3 x a day. The xstampa does NOT WORK AS WELL. Supposively u must eat high fat foods to make it more effective. I dont eat high fat foods for health reasons. I wish i could go back to oxycotin.

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Re: Flormart (# 52)

We need to remember that medications work differently in different people. We metabolize medications differently, so what works for one person may not work for others. Good luck, hope you find relief.

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Why are insurance companies making pts switch from oxycontin to extampza it has so many bad side effects? People please be careful ... Extampza sent me to the ER because of the numerous side effects.

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Re: CHAD from Kentucky (# 57)

I have been on regular oxycodone instant release for approx 4 yrs now and it works best for me. 30mg tabs every 4 hrs. I had gone to a couple diff Pain Mgt Specialists in past....both said only give extended relief meds. I cannot take ANY extended release meds of any kind because my body chemistry absorbs it all at once like an instant release tablet. There are others like me who have the same issue and cannot take these ER pain meds....if I took for example an oxycontin 80 mg tab .....the whole 80 mg would hit my body at once and I could be in dire consequences....so all the pain specialists in my area do not give anyone IR meds.....I also found all pain docs the meanest, rudest docs I have ever been around....at least in my area....you ought to hear their patients complain about how they are treated. These docs think we are all drugheads. Thankfully I get my med from my reg doc who will not force me into only seeing these a**holes. One of them totally insulted me on a 1st visit I told him I was going directly to pres of hospital. I did just that on the spot and I know this doc got yanked in by the prez and was told never talk like that again to any patient or get fired. I wanted to grab this doc by his necktie when it happened but I of course did not. These pain docs are the very worst people with pain can go to....they are biased against most of us and and some act like are a God to you. I do not, will not take any of their crap again and never let them talk down to any of you. We deserve to be treated with fairness!

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