2017 Adderall Not Working (Page 4)

I've noticed that the last three years in a row around this time either at the Adderall generic Sandoz brand is on backorder or suddenly the pills don't have the same affect. So in essence the pharmacy and drug manufacturers I getting paid while patients suffer without the proper medication. Has anyone else had this happen this month? I am taking the Adderall generic 30 milligrams twice a day I feel like I haven't taken anything.

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REPORT

Here is how it works: when a generic company decides it would like to supply a brand new medication, they conduct studies on a —-very small—group of people.

(Poor external validity)

The specific results of these tests are not made available to the public, only to the FDA.

The FDA must take “the word” of the generic company in terms of the validity of their testing

Once a generic company is approved, oversight by the FDA to ensure bioequivalency is very rare

I find this profoundly disturbing

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Re: Slisap03 (# 2)

Puts me to sleep also. A deep sleep. This brand uses NDC# manufacturer is in India

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Re: Jackie (# 56)

Excellent post. It's not you, even though that's what those in power want us ALL to believe. "Opiate Epidemic" my arse. Anyone at a wise age remembers when they were screaming "Opiate epidemic!!!" back in the 1990s. It's all a poor excuse to reduce the quality of needed medications and then ensure that patients point fingers at each other (as well as blame those sadly self-medicating only to end up in jail while actual rapists, child abusers, and other violent trash are more likely to get signed to a record label to gleefully detail their sadism over crappy automated backing tracks than serve any time) instead of trusting themselves AND each others' perceptions and then uniting for a common cause.

My older friends and relatives have also detailed the decline in efficacy (and outright phasing out) of formerly reliable "scheduled" medications prior to my own adulthood! The "War on Drugs" has now taken aim at relief-bringing medications as well as serving as an excuse to hand the government more power over what we can put into our bodies than OUR DOCTORS--the actual men and women with medical knowledge. It is absolutely enraging, and not only do we have little recourse, but we also do not have any ability to make this situation more widely known, as the media has no interest in reporting on issues that pretty much impact those on the "wrong" side of 30. The talentless reality teevee star bimbo's new plastic surgery and her imbecile-level IQ wife-beating thug of a boyfriend's latest monosyllabic grunts are far more important.

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I get 20 mg Teva from Walgreens and this month I have been falling asleep at my desk. It’s bad. I go to pain management for spine issues and they give me U/A's all the time. Tomorrow I am going to ask him specifically about my Adderall levels & then next time I go. After this I will probably check the Aurobindo because I am convinced they’re totally fake. I have some left over from months ago from Rite Aid that I stopped taking because they made me feel like s***. I’ll let you know how my drug panels look.

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Re: Sleepy (# 64)

I’m anxious to see what it says! But tbh, I used to go to a doctor that prescribed a multitude of controlled substances and had that drug testing contract set up with any controlled substance users. I was only taking Adderall. I took one 10mg pill, went to see him and did the test. And unbelievably, there was NO Adderall appearing on my test! I was like I just took it when I left my house an hour ago! I had to produce the bottle with the amount of appropriate pills left, etc. Fortunately, he believed me when I explained I take my medicine as prescribed! I have/had no explanation as to why nothing came up, NONE. But what I’m trying to say is, I wish there was a way to actually test the pills!

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Re: B (# 65)

There used to be a place you could send them for testing, back when mdma pills were popular in clubs. Went yesterday and Tevas from a couple months ago are fine. I get tested again next week and will check the s***ty Aurobindo's next. I am not sure how reliable their tests are though. I have a cannabis card and according to my levels he says I am just at the point of getting “high”. I don’t know what he means since I blaze all the time & it’s dispensary stuff, but he said my Adderall levels are the same as the prior tests. I will update you next week.

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Re: Jackie (# 56)

I agree a million times with your post! I too am 43, helped by brand Adderall and prescription opiates, never felt an ounce of "energy" or "euphoria", just help with ADHD and pain! No escalating doses, negative consequences on my life, "hyperalgesia" or any of the crap the mainstream media has been pushing the last few years to force doctors to switch patients from DIRT CHEAP opiates (which, aside from constipation, are harmless to the body providing one isn't unnecessarily yanked off them...SSRIs cause dependency and withdrawal too, and no one sees those on antidepressants being called "junkies" in part because they still give profit to Big Pharma) to more expensive, profit-making yet dangerous drugs like biologics which decimate your immune system (and that's the feature, not the bug!) and marijuana, which was the "medically incorrect" demon a decade ago that opiates have become now! It's no coincidence why: now that marijuana is legal in many states, it is now a profitable venture, so it's being (ridiculously) touted as a cure-all for severe pain to replace opiates!

Pot makes me non-functional, makes my ADHD symptoms a million times worse, and Does nothing for pain. I won't go near the stuff and all I hear is "try another kind", "try a different ratio", "try vaping/edibles/tinctures" blah blah blah. I hate the stuff but recognize that everyone's body is different. If only the mainstream media didn't pull the snow job that "opiates don't really kill pain" (people are so naive these days) in cahoots with Big Pharma, the FDA, and the DEA to threaten doctors who don't buy in to their unscientific BS that contradicts evidence from hundreds of years of medicine.

As for Adderall, you are 100 percent right and the two situations are linked. There are several patents on the web that speak of "additives to reduce the abusability of stimulants and other scheduled drugs". They aren't just talking about delayed release here. I believe this, combined with DEA/FDA shenanigans (lowering amount of amphetamine or precursors released to pharmaceutical manufacturers/not inspecting the poor practices of pharmaceutical manufacturers in India and China) and Big Pharma push to get people off patent-expired Adderall and onto the extended release new patent holders which cause tons of side effects) have created a perfect storm. And also the perfect out--just call anyone who complains a "conspiracy theorist" or a "junkie"!

Remember, the vast majority of people are authoritarian followers who believe EVERYTHING they are told while being alienated from their own perceptions. Those like us don't, so don't let them make you doubt your own body.

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I have been on Adderall since like 2001 before that I was on provigil, but yes the Adderall is getting crappier and crappier by the yr! I get 90 pills a month 20mgs and they work for like 3dys after I get them filled and then i start to feel like I didnt take anything again. I hate the orange generic ones , lately I've been getting white ones or yellow. But none of them work like they used to. And I run out always like 1 week or 2weeks to soon and spend my days In bed because the withdrawals are very bad from being on them for so long, I cant think about doing anything I don't do anything for the first like 2dys but go to bathroom and get small things to eat. Nobody cares the government let's the genetics be only 40% of the drug I think and the rest fillers so different ones have different levels its BS!

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The following is My personal experience only:

I'm in my third year now taking Adderall for Adult ADD Inattentive. I have never taken Brand or XR, only 20mg IR or 30mg IR generic Mixed Amphetamine Salts. The Manufacturers I've used include Teva, CorePharma, Aurobindo, Sandoz, Actavis, Mallinkrodt...basically all of them. Some better results than others, but ALL of them had one common thread. And that is...of the 30 days in a month, all of the generic Adderalls, for me, will lose efficacy as the month goes on. By the 15th of the month, I feel like I'm taking a sugar pill and curiously, I notice that the texture of the tablet is deteriorating from firm and sleek to chalky and crumbly. Every month....same thing. I spend many hours in my car for work, and I always have my medications in a black attaché case with me. I began to notice how much high heat my meds were being exposed to. On One unusually, scorching hot day recently, as I was fishing out pills from the bottle, a few of the Aurobindo generic 30mg IR tablets had actually crumbled so much, they were now at the bottom in tiny pieces and fine dust. What? That night, on a whim, I took all my meds out of my briefcase and put them in the fridge on a low cooling setting and left them there overnight. The next morning, all of the remaining Aurobindo tablets were sleek and shiny again and doses from that day forward always "work"...almost like they did in the early days. My conclusion is:
If subjected to high temperatures or direct sunlight for an extended period of time, the active ingredients in generic Adderall IR, (L-Amp and D-Amp), will lose their efficacy to the point that it does feel like I'm taking a sugar pill every dose from middle of the month until next fill date. I now put my Adderall (from any manufacturer) in the fridge every night and today it is "working" much, much better. Almost like the early days.

This is my personal experience only. I have no scientific evidence or any proof that my conclusions will affect others taking this medication in a similar manner.

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Re: Slisap03 (# 2)

Yes I take 10mg twice a day and I too get very tired and want to sleep. Not always but it happens and I thought what I need to up my dose. I have been on 10mg for about 3 yrs. and sometimes I do take one and a half at times.

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Re: allie (# 14)

I’m not sure which company makes my blue 10mg but I noticed it has been making me depressed too.

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Same here, past 3-4 years the meds have gone bad and adverse side effects then cause major fatigue! Meds are not the same anymore. I’ve had 4-5 meds majorly hit all at once...now it’s my Dava pharma Xanax and now my dr who had a consent order is retiring cause he’s an internal medicine dr, not a specialist, and didn’t know certain meds are now an agenda to bump disabled and Medicaid people off. Pharma is an agenda to bump people off! After what I’ve been through it’s so clear you got each medication doing the opposite of what you got it for! And I’ve never had issues going back to 1991, 2003 and 2006 for each medicine... 1991 for ADD meds.

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ABSOLUTELY fantastic investigative journalism AT ITS BEST. Years and YEARS of research and investigation. We have ALL been suspicious of THIS...and some of us have found out some of these details in bits and pieces of various information, on all of the various "my generic adderall is not working" forums threads and posts all over the interweb.

HERE IS PROOF. and. Finally.. a book!

EVERYONE HERE AND ALSO EVERYONE ON THE HUNDREDS OF OTHER THREADS ABOUT GENERIC ADDERALL BEING S*** NEEDS TO LISTEN TO THIS INTERVIEW, AND IF POSSIBLE EVEN READ THIS BOOK. WOW.

WE ARE NOT CRAZY.

The book is: Bottle of Lies by Katherine Eban

There is a podcast interview on NPR you can listen to but I also found this interview on youtube with the author.

Watch "Bottle of Lies: How Poor FDA Oversight & Fraud in Generic Drug Industry Threaten Patients’ Health" on YouTube

https://youtu.be/lCrTuT5ywvI

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Re: GenXGuyInMillennihell (# 67)

I agree with you 100%.
The medication I take works for me because I don’t “feel” anything from it.

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Generic is a s*** show. Generic Klonopin is also garbage. I saw on the news that there is no FDA oversight when these generic pills come from other countries. One person went to the ER and had 0 benzo's in his urine so he was taking nothing. Same thing happened to me and it's not just benzo's its GENERICS in general now. CVS will not let me have my .5 mg Klonopin (NAME BRAND) AT BEDTIME ONLY, until I run out! When I took the generic I could get it 12 days early because it was nothing. I had to cancel a vacation over not being able to get me prescription ONE day early. Prisoners in our homes over a prescription is insanity.

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Re: KerryAnne (# 73)

"Generic" by Katherine Eban is indeed a fantastic book. Everyone should read it. It explains so much about why our medications stopped working or started having negative effects. I just wish there was a way to stop this.

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Re: fromnyc (# 20)

I have been on amphetamines since 1969 to 1973 every day (Vietnam era USAF E-5 Staff Sgt) & again, from June 1994 every day until, this writing January 6th, 2021. I realize this topic is strictly on Adderall (mixed amphetamine salts).....don't want to steer too far away from the topic........

I took Adderall brand name (1997 to 2007) by Richwood Pharma Co (Kentucky) 1997 to around 2002, later brand name Shire US 10 mg. until 2007, then, switched to Barr Labs, in 2007, later, after Teva bought Barr Labs (Sellersville PA USA) NDC 0555-0972-02 100 tabs ten mg until January of 2014. They all worked satisfactory for me. In the here and now the Teva generic DextroStat, are not as strong as they were 20 yrs ago, (but it might be in my head) I tried them for about 6 months, and they kicked in within 30 min vs todays Teva Dextroamphetamine takes about 1 hr minimum.

My insurance co. took them off the formulary Jan 2014 I/R for generic, which I switched to around 2008 to 2014 & it was excellent for my ADHD & my treatment resistant Depression. As everyone knows, the USA pharma industry radically changed for the worse, price fixing, DEA mandatory quotas, was it around 2017? What did I do? My last 100 Adderall generic costs me cash over $225.00 in Jan 2014 from a independent owner pharmacist !! (100 tabs x 10 mg)

My last shrink who took care of me for the past 21 years, allowed me to switch to 10 mg. of generic DextroStat, a/k/a dextroamphetamine 10 mg instant release, in March of 2014 to Dec of 2019 when he retired. (Was on 10 mg x 4 tabs of Adderall 1997 instant release, by 2014, I was reduced to 30 mg of dextroamphetamine sulfate I/R pure, (d-dex), later, to x two x 10 mg. 2017 to 2019/2021.

I submit to you back in the day, the ratio of amphetamine resin (base) was a ratio of 1, on a microgram, or milligram basis, vs. d-amphetamine (dextroamphetamine) I/R 3, meaning 3 times stronger than base amphetamine sulfate, vs. methamphetamine a "5" meaning 5 times stronger than base amphetamine sulfate. (Because I took either Benzedrine, or Dexedrine or Desoxyn in the 1970's !!!

My CVS pharmacy were sold out of Generic Dextrostat, (dextroamphetamine sulfate mfg of my choice was Teva/Barr 10 mg. and pharmacists told me when the wholesaler delivered the product he hoped in January 2021 to CVS in Charlotte, North Carolina, he promised me he would be sold out within 72 hours, due to the demand !! on Dec 5th, of 2020 !!!! Thank the DEA quotas for this.

I have a PCP who has my medical records who wrote me a script for 180 x 10 mg of my instant release dextroamphetamine tabs. I returned to a rare independent pharmacy, who knows me, personally from years ago, and, they told me, they would special order me either Teva Barr from a different "unfriendly wholesaler" or the same wholesaler, did also carry Mallies, and, I agreed to pay up front, US over $300.00 for 72 hour service for 100 x 10 mg of the Mallies, hdqtrs St Louis, Missouri. I am old enough to be on Medicare, and my usual costs the past 3 yrs are only US 7.00 for 90 tabs of any generic Dextroamphetamine sulfate I want. My bottle of Richwood Adderall 10 mg has a NDC #58521-032-01 (100 tabs x 10 mg) I have about 50 tabs left. And I am Sad !!!

I submit to you, I squirrel away emergency meds, and I had a full bottle of factory sealed 100 ct of Richwood Adderall, 10 mg mfg date 1997 expiration date 2000. Stored in my dark closet, low humidity no sunlight, for a rainy day, for the past 22 years. I compared & finally opened the bottle of my last stored bottle of either Richwood Adderall brand name 10 mg or my Dexedrine brand name, of pink orange E-19 Glaxo Smith Kline 5 mg, also issued in the 1990's. Here are my results:

1/2 tab (5 mg of original brand formula of Adderall) are as strong as fresh Mallinckcrodt 10 mg of dextroamphetamine, which are supposed to be 1/2 of the formulation to be much stronger mg for milligram !! Why? I have experimented every AM at wakeup and the 22 yr old brand Adderall 1/2 tab of a 10 mg kicks in within 20 minutes, vs. the fresh dextroamphetamine I/R kicks in at least 1 hour to 1.5 hrs always on a empty stomach. Both peter out about the same 4+ hrs later.

Therefore........I agree with the other posters here, there is a "huge difference" in the bioavailability of how our bodies process the stimulants, vs, 1960's to at least 2012 to 2014. that is over, 50 years. I also blame our USA govt, and the greedy pharma mfgs, and I have lost all trust in the FDA, and I do not like the DEA. Even the "bioequivalence" of the FDA standards imho can be screwed with by cheap fillers and binders. as imho the pharma mfg and the retail pharma firms have sold out the very cheapest pill of the month for all of us ADHD or Narcolepsy sufferers !!! (to the price sensitive retail chain pharmacies) !!!

Just do your research on Teva/Barr guilty pleas by dozens of US states in lawsuits to over 4 to 6 mfg of price fixing that began around 2012 to 2015+, and the massive layoffs of ten of thousands of employees + executives walking off the job out of disgust !! Finally did you know that the Sherman Act was invoked to force Teva/Barr to abandon the production of generic I/R Adderall to farm it out, with little control over the quality standards to who knows who actually manufacturers the present diminished quality of once stellar Adderall brand or generic of I call yesteryear. Imho the stimulant industry has gone to He*l in the past 10 years ! End of my rant !

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