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100mg Zoloft Equivalent To How Much Effexor

Updated June 24, 2015
TMomm Says:
Mon, June 22, 2015

My Dr switched me from 37.5 mg of Effexor to 100 mg of Zoloft. I told him Effexor made me tired. So he says Zoloft should make me have more energy. I was down to 37.5 Effexor from 75mg because I was trying to wean off. Now I feel like I am on a higher dosage than I was before. Plus I've gained weight. I don't feel anymore energetic either. Is 37.5 mg Effexor equivalent to 100mg Zoloft? If it's a higher dose then I'm not happy.

1 Reply

1
Verwon Says:
Wed, June 24, 2015

Hello, TMomm! How are you?

They are actually different classes of medications. Effexor is an SNRI antidepressant, while Zoloft is an SSRI.

And the dosing is approximately correct, so you're really not on a higher one.

The FDA lists the typical side effects of Zoloft as possibly including nausea, dizziness, headache, dry mouth and weight changes.

What makes you feel that you're on a higher dose? It could just be the switch that's causing these symptoms.

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