Has anyone had this new pain medicine called Zilretta for knee pain? This is a newly approved medication and I have not been able to find any patient's comments. ## This brand name is new, but the active ingredient isn't new, it's Triamcinolone. it is a steroid class medication that is used to treat allergic reactions, immune disorders, and inflammation. The FDA lists its typical side effects as possibly including administration site reaction, redness, soreness, and irritation. Can anyone that's been on it chime in with their experience?