I'm planning on using 80% TCA trichloroacetic acid in xanthelasma palpebrarum. Several articles compared the efficacy of 3 different strengths including 100% with excellent results. I;m looking for other who have experience with this treatment. CONCLUSION: 100% TCA gives the best results in papulo-nodular lesions, 100% or 70% TCA give similar results in flat plaque xanthelasma and in macular lesions 50% is sufficient. Hypopigmentation is the commonest side effect, followed by hyperpigmentation. Scarring is a minor problem.