which is the best medicine for itching?? ## Sarna Lotion. You can find it at the pharmacy or your local supermarket's medicine section, normally. It's about 13 bucks and the ONLY thing that got me through P.U.P.P.P.s when I was eight months pregnant with twins. It stands for Pruritic Urticarial Postules and Plaques of Pregnancy. Very big name for an insanely itchy rash that NEVER stops itching no matter what you do. Birthing the baby/babies is the only known cure, but Sarna lotion was my saving grace-it made it so i felt like a human being again. Very soothing and like...manna from heaven but for itchy skin. hope this helps.