I have been taking this drug (Orasone) for years off and on (the 10 mg pill) for asthma and found that it's also excellent for allergies, itching or rashes. Most of that was caused because of an over active immune system along with antibiotics. Has anyone else had a positive experience with Orasone? ## Hello, Ed! How are you? I'm very glad that it's working so well for you. Orasone contains the active ingredient Prednisone, which is a steroid class medication. It is often used to treat severe allergy issues that aren't responding to other medications, because it can help with the swelling that allergic reactions can cause, plus they can dampen your immune system to help stop the allergic response. However, with long term use, it can leach calcium from the bones, making t...