am curios as to wjhat the ingredients in lodine xl are can any one tell me ## The active ingredient in Lodine XL is Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) - effective in treating pain and inflammation in the body. To view more information about this drug click on the link below... Do you have any more questions or information to add? Please post back if you do.