I am currently using fluconazole while a orthopedic (hip) spacer is in my leg following a severe infection that formed in my prostetic hip.Due to my inability to walk(toe touch only),I have gained weight ,but have also developed two staph infections in my foot and theigh,,,,,is this normal? ## I wouldn't say any type of infection is normal, since they have the potential to be dangerous. As to the Fluconazole, it is an antifungal medication, so whether or not it will help depends on the specific type of infection you have. When treating staph, it is usually used in combination with other medications. Ref: Medline Plus Fluconazole The FDA warns that Fluconazole may cause side effects, such as nausea, dizziness, headache, and diarrhea. Are you on any other medications?