Anyone on Dificid for c-diff? Is it working for you? How are the side effects and how long does it take to work? This is possibly my second c-diff infection and I'm waiting for the test results. I'm really scared as I hear this infection can be deadly. My med for my first infection was Flagyl. Please help me ease my anxiety. ## Hi Janet, Sorry to hear about the C. diff infection. I pray that you get well soon! While I haven't experienced anything quite like that, I did see a comment from a (alleged) pharmacist stating that Dificid (fidaxomicin) should start to work within a few days. So maybe you just need to take it for a little while longer before it can kick into full gear? As far as side effects go, someone's who actually taken it may have a better idea of what to ex...