I have degenerate disk problems, a knee replacement, as well as arthritis, and I can't get any muscle relaxer that actually works. Why? ## Well when you bones have structure issues the muscles try to hold the cartilage & ligaments that's left in place .... when a muscle reader relaxes the muscles it may relax the muscles but it removes the support of the cartilage & ligaments & transfers the stress points to those connective tissues & being in same proximity it just appears that the relaxers are not working .....imo ## What are you expecting them to do? They are not pain relievers, and will only work to help relax muscle tissue, none of the conditions you've mentioned are muscle based, so a muscle relaxant won't help much with any of them. Ref: Muscle Rel...