Hydrocodone And Oxycodone Side Effect Intolerance


I have taken Hydrocodone 10/500 for years on and off. Not dependent. The worst side effect was head itching. tolerable. I was off and recently prescribed 10/325. The itching is head to toe unbearable. I have scars from scratching. It lasts for days with very little help from Benadryl 50 mg. every 6 hours. My doctor said Oxycodone 10/325 will be better. I took it after a meal. One to two hours later I am very nauseous. 3-4 hours latter headache and intense itching. 13 hours later I still feel sick from it. When I need pain medication I need it badly. I can't suffer in bed all the time. Help please. what are my alternatives?

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Hello, Bon! How are you?

There are quite a few others available, such as Opana, Dilaudid, Fentanyl and Morphine. The FDA lists all of these as being narcotic analgesics, so they have the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

It is most likely a matter of working with your doctor to find one that works for you, without making you so miserable. Trial and error is sometimes necessary.

Does anyone else have any ideas?

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I switched meds on monday from Hydrocodne/Acetaminophen 10mg-325mg to Oxycodone/Acetaminophen 10mg-325mg and today is thursday. Since then, I experienced insomnia and high anxiety whenever i tried to lay down. I also had nervousness and was pacing a lot. When sitting up in a chair i doze out, but it is not being able to sleep comfortably in my bed that has become a nightmare.

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