Efudex Treatment Effects (Top voted first)

I have used Efudex for four weeks and i now have a lump with a hard crust around it, and it is sore and itchy. What should i do?

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Hello, Judy! How are you? Have you informed your doctor, yet?

The U.S. FDA does list the dryness/crusting as being possible side effects of using it. It may also cause abdominal pain, headache and mouth sores.

How long has your doctor instructed you to use it?

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Medline Plus states "If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil. If you are using fluorouracil to treat basal cell carcinoma, you should continue using it until the lesions are gone. This usually takes at least 3 to 6 weeks, but may take as long as 10 to 12 weeks."

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Can I use Polysporin ointment on the oozing areas after Efudex treatment is finished as a precaution?

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Re: Roy (# 2)

I was prescribed Efudex for squamous cell carcinoma. The Dr first did a scraping then I started the cream for 3 weeks. I have what looks like a couple of actual holes in my skin?? The crustiness is still there. Any ideas?

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